Merck
CN

R3250

Sigma-Aldrich

视黄醇乙酸酯

synthetic, matrix dispersion, 475,000-650,000 USP units/g

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别名:
维生素 A 醋酸酯, 醋酸维生素 A
经验公式(希尔记法):
C22H32O2
CAS号:
分子量:
328.49
Beilstein:
1915439
EC 号:
MDL编号:
eCl@ss:
34058009
PubChem化学物质编号:
NACRES:
NA.79

生物来源

synthetic

质量水平

形式

matrix dispersion

比活

475,000-650,000 USP units/g

颜色

yellow

mp

57-58 °C

储存温度

−20°C

SMILES字符串

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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相关类别

一般描述

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.

应用

Retinyl acetate has been used:
  • a control diet to study its effect at different developmental periods in fish larvae
  • to study its inhibitory effects on Mycobacterium avium subspecies paratuberculosis (MAP) strains
  • as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk

生化/生理作用

Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as required. Retinyl acetate is used in a wide range of biological applications. It acts as a chemopreventive agent. Retinyl acetate also has antineoplastic property.

外形

Dispersion in cornstarch-gelatin matrix. Oil dispersible

分析说明

Activity based on HPLC comparison to USP standard.

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Aquatic Chronic 4 - Repr. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


分析证书(COA)

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Intake of high levels of vitamin A and polyunsaturated fatty acids during different developmental periods modifies the expression of morphogenesis genes in European sea bass (Dicentrarchus labrax)
Villeneuve LAN, et al.
The British Journal of Nutrition, 95(4), 677-687 (2006)
Laure A N Villeneuve et al.
The British journal of nutrition, 95(4), 677-687 (2006-03-31)
The effect of the feeding period on larval development was investigated in European sea bass larvae by considering the expression level of some genes involved in morphogenesis. Larvae were fed a control diet except during three different periods (period A:
Therapeutic Use of Medicinal Plants and their Extracts:Phytochemistry and Bioactive Compounds (2018)
Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid
Udeani GO, et al.
Cancer Research, 57(16), 3424-3428 (1997)
Effect of combined selenium and retinyl acetate treatment on mammary carcinogenesis
Thompson HJ, et al.
Cancer Research, 41(4), 1413-1416 (1981)

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