R5143
芸香素 水合物
≥94% (HPLC), powder
别名:
Quercetin-3-rutinoside 水合物, Vitamin P 水合物
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关于此项目
经验公式（希尔记法）:
C27H30O16 · xH2O
化学文摘社编号:
分子量:
610.52 (anhydrous basis)
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-814-1
Beilstein/REAXYS Number:
75455
MDL number:
Quality Segment
assay
≥94% (HPLC)
form
powder
color
yellow to green
mp
195 °C (dec.) (lit.)
solubility
pyridine: 50 mg/mL, DMSO: soluble, aqueous base: soluble
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
[H]O[H].O[C@H]1[C@H](OC[C@H]([C@H]2O)O[C@@H](OC(C3=O)=C(C4=CC=C(O)C(O)=C4)OC5=C3C(O)=CC(O)=C5)[C@H](O)[C@H]2O)O[C@H]([C@@H]([C@H]1O)O)C
InChI
1S/C27H30O16.H2O/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9;/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3;1H2/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-;/m0./s1
InChI key
PGHSKTKIQIBATG-ZAAWVBGYSA-N
General description
Rutin hydrate has radioprotective and antiplatelet activity. Rutin reduces hepatic and blood cholesterol levels.
Application
Rutin hydrate has been used:
- as an inhibitory compound against Skeletonema costatum
- to analyze the phenolic component and antioxidant activity of nettle
- to assess the flavonoid content in Propolis
Biochem/physiol Actions
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodiumethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves