R5903
Anti-Rab11 antibody produced in rabbit
1 mg/mL, affinity isolated antibody, buffered aqueous solution
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
rat, mouse, human
Citations:
12
Technique(s):
western blot: 6.6 μg/mL using HeLa cell extract
Uniprot accession no.:
产品名称
Anti-Rab11 antibody produced in rabbit, 1 mg/mL, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat, mouse, human
concentration
1 mg/mL
technique(s)
western blot: 6.6 μg/mL using HeLa cell extract
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RAB11A(8766)
mouse ... Rab11a(53869)
rat ... Rab11a(81830)
Biochem/physiol Actions
Rab11a (Ras-related protein Rab-11A) participates in the modulation of basolateral to apical transcytosis. It controls TRPV5/6 (Ca2+-selective members) channel trafficking. It is essential for the production of bile canalicular in WIF-B9 cells (rat hepatoma/human fibroblast hybrid cells).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Application
Anti-Rab11 has been used in western blotting and immunohistochemistry.
General description
Rab11 (Ras-related protein) has three subtypes -Rab11a, Rab11b, and Rab25. Rab11a (Ras-related protein Rab-11A) belongs to the ras-like small GTP-binding protein superfamily. It is found in nonpolarized cells like fibroblasts and erythroleukemia cells. It is located on human chromosome 15q21.3-q22.31 and on mouse chromosome 9. Rab11a is expressed abundantly.
Immunogen
synthetic peptide corresponding to amino acid residues 1-17 from human Rab11. This sequence is completely conserved in human, mouse, and rat and 94% conserved in C. elegans and amphibians.
Physical form
Solution in phosphate buffered saline containing 1 mg/mL bovine serum albumin and 0.05% sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells
Kallquist L, et al.
Experimental Cell Research, 316(19), 3182-3196 (2010)
O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function
Muller J, et al.
PLoS ONE, 9(2) (2014)
Human rab11a: transcription, chromosome mapping and effect on the expression levels of host GTP-binding proteins
Gromov PS, et al.
Febs Letters, 429(3), 359-364 (1998)
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
Husebye H, et al.
Immunity, 33(4), 583-596 (2010)
Regulation of vesicle trafficking in madin-darby canine kidney cells by Rab11a and Rab25
Wang X, et al.
The Journal of Biological Chemistry, 275(37), 29138-29146 (2000)
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