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Merck
CN

R6527

Reboxetine mesylate hydrate

>96% (HPLC), noradrenaline uptake inhibitor, solid

别名:

(2R)-rel-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine, Edronax, Vestra

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关于此项目

经验公式(希尔记法):
C19H23NO3 · CH3SO3H · xH2O
化学文摘社编号:
分子量:
409.50 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
>96% (HPLC)
Form:
solid
Storage condition:
desiccated
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产品名称

Reboxetine mesylate hydrate, >96% (HPLC), solid

Quality Segment

assay

>96% (HPLC)

form

solid

storage condition

desiccated

color

white to tan

solubility

H2O: >5 mg/mL at ≤60 °C

shipped in

wet ice

storage temp.

2-8°C

SMILES string

O.CS(O)(=O)=O.CCOc1ccccc1O[C@@H]([C@H]2CNCCO2)c3ccccc3

InChI

1S/C19H23NO3.CH4O3S.H2O/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4;/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4);1H2/t18-,19-;;/m1../s1

InChI key

SZPHEVAYLIVGRC-BAMQSBMESA-N

Application

Reboxetine mesylate hydrate has been used as a selective norepinephrine transport blocker:
  • to study its effects on the surge of dopamine in the cortex of mice brain
  • to study its anti-immobility effects on the behavior of mice
  • to analyze its effects on the probabilistic reversal learning task in rodents

Biochem/physiol Actions

Reboxetine mesylate hydrate is a selective noradrenaline uptake inhibitor.
Reboxetine exhibits anti-depressant activity.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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