产品名称
血管紧张素 II EIA 试剂盒, for serum, plasma, culture supernatant and cell lysates
species reactivity
mouse, human, rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
enzyme immunoassay: suitable
input
sample type cell lysate
sample type culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 2.62 pg/mL
standard curve range: 0.1-1000 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... AGT(183)
Application
仅用于研究目的。不用于诊断程序。
血管紧张素 II EIA 试剂盒已分别用于分析小鼠和大鼠循环和血清中血管紧张素 II (Ang II) 的水平。
血管紧张素 II EIA 试剂盒已分别用于分析小鼠和大鼠循环和血清中血管紧张素 II (Ang II) 的水平。
血管紧张素II EIA试剂盒用于定量估计血清血管紧张素II。
请参阅随附常规ELISA试剂盒 操作步骤(夹心式、竞争性 & 间接ELISA)
Biochem/physiol Actions
体外研究 表明,机械牵张诱导的血管紧张素 II释放在介导牵张诱导的肥大反应中起着至关重要的作用。血管紧张素 II参与维持血压,在高血压和心血管疾病的病理生理过程中具有重要作用。血管紧张素 II在血管平滑肌细胞的生长诱导、细胞迁移和有丝分裂中也有重要角色。它可增强成纤维细胞中 I 类型和 III 型胶原的生成,导致血管壁和心肌增厚以及纤维化。血管紧张素 II 基因的变异增加了心肌梗死、高血压和左心室肥厚的风险。血管紧张素 II 的表达与心力衰竭、心脏重塑、糖尿病以及动脉损伤的增殖和炎症反应有关。血管紧张素 II 转换酶抑制剂或血管紧张素 II 受体拮抗剂等药物可用于治疗血管紧张素 II 诱导的高血压和充血性心力衰竭。
General description
血管紧张素 II 酶联免疫分析 (EIA) 试剂盒是一种基于竞争酶联免疫分析原理的血管紧张素 II 多肽体外定量检测方法。EIA-ANGII-1 理论上可以检测所有活性血管紧张素,包括 ANGI、ANGII、ANGIII 和 ANGIV。但是,它不能检测无活性的血管紧张素原。
Immunogen
血管紧张素 II,合成肽
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
常规特殊物品
含少量动物源组分生物产品
此项目有
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