产品名称
Apelin EIA试剂盒, for serum, plasma, culture supernatant and cell lysates
species reactivity
rat, mouse, human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
enzyme immunoassay: suitable
input
sample type cell lysate
sample type plasma
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 5.84 pg/mL
standard curve range: 0.1-1000 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... APLN(8862)
Application
仅供研究使用。不可用于诊断过程。
Apelin EIA试剂盒已被用于确定脂肪前细胞生长培养基中apelin的浓度。
Apelin EIA试剂盒已被用于确定脂肪前细胞生长培养基中apelin的浓度。
Biochem/physiol Actions
Apelin（APLN）由白色脂肪组织分泌。它是一种在肿瘤细胞进程和血管形成中起作用的脂肪因子。该蛋白可能在肥胖相关疾病中起作用。APLN可参与调节能量稳态、水平衡、葡萄糖代谢和免疫力。它在许多癌症中显示出上调。
General description
Apelin C末端酶免疫测定（EIA）试剂盒是一种基于竞争性酶免疫测定原理，对Apelin C末端肽进行体外定量测定的方法。 EIA-APC-1试剂盒可检测所有活性Apelin肽，包括Apelin-13、Apelin-28、Apelin-31和Apelin-36。
Immunogen
Apelin，合成肽
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
常规特殊物品
低风险生物材料
此项目有
Bogusz Trojanowicz et al.
Toxins, 12(12) (2020-12-02)
Apelin peptides (APLN) serve as second substrates for angiotensin-converting enzyme 2 (ACE2) and, in contrast to angiotensin II (AngII), exert blood-pressure lowering and vasodilatation effects through binding to G-coupled APLN receptor (APLNR). ACE2-mediated cleavage of the APLN may reduce its
Assessment of Apelin Serum Levels in Persistent Atrial Fibrillation and Coronary Artery Disease.
Riazian M
The American Journal of the Medical Sciences (2016)
Serum apelin levels and body composition changes in breast cancer patients treated with an aromatase inhibitor.
Salman T
Journal of B.U.ON. : Official Journal of the Balkan Union of Oncology (2016)
Apelin Attenuates Oxidative Stress in Human Adipocytes*
Aung Than
The Journal of Biological Chemistry (2014)
Apelin as a marker for monitoring the tumor vessel normalization window during antiangiogenic therapy
Li Zhang
Cancer Science (2016)
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