RAB0019
人双调蛋白ELISA试剂盒
for serum, plasma, cell culture supernatant and urine
别名:
AR
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... AREG(374)
Input:
sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
产品名称
人双调蛋白ELISA试剂盒, for serum, plasma, cell culture supernatant and urine
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 10 pg/mL
standard curve range: 16.46-4000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... AREG(374)
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Application
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Amphiregulin ELISA Kit has been used to estimate the plasma concentration of amphiregulin by ELISA.
Human Amphiregulin ELISA Kit has been used to estimate the plasma concentration of amphiregulin by ELISA.
Biochem/physiol Actions
Areg (amphiregulin) stimulates growth-signaling pathways via EGF (epidermal growth factor) receptors. Areg participates in the organogenesis of mammary gland. It is regarded as a pro-oncogenic factor and contributes to tumor progression. Upregulation of the AREG gene is observed in cancer and resists chemotherapy. AREG reduces E-cadherin expression in order to promote invasion and progression of ovarian cancer.
General description
The Human Amphiregulin (AR) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human AR in serum, plasma, cell culture supernatants and urine.
The AREG (amphiregulin) gene codes for a shedding ectodomain, derived from a transmembrane precursor of 252 amino acids. The encoded protein is released into blood or cellular vicinity through autocrine and paracrine. Areg is predominantly expressed in epithelial, mesenchymal cells and also by active immune cells. The AREG gene is mapped to human chromosome 4q13.3.
The AREG (amphiregulin) gene codes for a shedding ectodomain, derived from a transmembrane precursor of 252 amino acids. The encoded protein is released into blood or cellular vicinity through autocrine and paracrine. Areg is predominantly expressed in epithelial, mesenchymal cells and also by active immune cells. The AREG gene is mapped to human chromosome 4q13.3.
Immunogen
Recombinant Human Amphiregulin
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
Predictive blood plasma biomarkers for EGFR inhibitor-induced skin rash.
Hichert V, et al.
Oncotarget, 8(21), 35193-35193 (2017)
Abnormal amphiregulin expression correlates with gastric cancer prognosis.
Wang B, et al.
Oncotarget, 7(47), 76684-76684 (2016)
Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.
Cheng J C, et al.
Oncotarget, 7(49), 81645-81645 (2016)
Correlation between Trop2 and amphiregulin coexpression and overall survival in gastric cancer.
Zhao W, et al.
Cancer Medicine, 6(5), 994-1001 (2017)
Masaru Karakawa et al.
Journal of cellular physiology, 229(12), 1935-1945 (2014-04-09)
The cutaneous T cell-attracting chemokine (CTACK)/CCL27 is indispensable in skin inflammation. CTACK/CCL27 is exclusively produced by epidermal keratinocytes to attract CCR10-expressing T lymphocytes to the skin. We investigated the mechanism of CTACK/CCL27 production from normal human epidermal keratinocytes (NHEKs) by
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持