产品名称
小鼠MIP-3 β / CCL19 ELISA试剂盒, for serum, plasma and cell culture supernatant
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 4.1-1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Ccl19(24047)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
C-C motif chemokine ligand 19 (CCL19) acts as a chemoattractant for T and B lymphocytes, dendritic cells, macrophage progenitor cells and natural killer cells. Therefore, this protein might play an essential role in migration of T cells in the thymus and transfer of T and B cells to secondary lymphoid organs. Overexpression of MIP-3 β (macrophage inflammatory protein-3β)/ C-C motif chemokine ligand 19 (CCL19) leads to pulmonary sarcoidosis.
General description
C-C motif chemokine ligand 19 (CCL19), also known as macrophage inflammatory protein (MIP)-3β, is encoded by the gene mapped to human chromosome 9. The encoded protein is specifically expressed in lymphoid tissues.
The Mouse MIP-3-β (Macrophage Inflammatory Protein 3 β) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MIP-3- β in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Mouse MIP-3 β
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8B - Non-combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Expression of macrophage inflammatory protein-3 beta/CCL19 in pulmonary sarcoidosis.
Gibejova A
American Journal of Respiratory and Critical Care Medicine, 167(12), 1695-1703 (2003)
CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells.
Marsland BJ
Immunity, 22(4), 493-505 (2005)
The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment.
Baekkevold ES
The Journal of Experimental Medicine, 193(9), 1105-1112 (2001)
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