产品名称
人MCP-3 / CCL7 ELISA试剂盒, for serum, plasma, cell culture supernatant and urine
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 24.58-6000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CCL7(6354)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Monocyte-chemotactic protein 3 (MCP3), also known as chemokine (C-C motif) ligand 7 (CCL7), has an ability to attract and activate a large panel of leukocytes including monocytes, eosinophils, basophils, dendritic cells, natural killer cells and activated T lymphocytes. This property of the protein makes it favorable for antitumor therapy. Mutation in the gene is associated with the development of Crohn′s Disease (CD). Elevated expression of the gene contributes to the development of gastric cancer (GC). Thus, it acts as a potent diagnostic marker for GC.
General description
The Human MCP-3 (Monocyte Chemoattractant Protein-3) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human MCP-3 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human MCP3
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
CCL7 and CCL21 overexpression in gastric cancer is associated with lymph node metastasis and poor prognosis
Hwang TL, et al.
World Journal of Gastroenterology, 18(11), 1249-1249 (2012)
MCP?3 (CCL7) delivered by parvovirus MVMp reduces tumorigenicity of mouse melanoma cells through activation of T lymphocytes and NK cells
Wetzel K, et al.
International Journal of Cancer. Journal International Du Cancer, 120(6), 1364-1371 (2007)
The Genomics of Autoimmune Disease in the Era of Genome-Wide Association Studies and Beyond
Lessard CJ, et al.
Autoimmunity Reviews, 11(4), 267-275 (2012)
相关内容
Instructions
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