RAB0098
人M-CSF / CSF1 ELISA试剂盒
for serum, plasma, cell culture supernatant, urine
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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... CSF1(1435)
Input:
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type urine
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
产品名称
人M-CSF / CSF1 ELISA试剂盒, for serum, plasma, cell culture supernatant, urine
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.78-2000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CSF1(1435)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
M-CSF (colony stimulating factor 1) plays a major role in the immune response, bone metabolism and the development of some cancers. It modulates macrophage survival, proliferation, differentiation and chemotaxis.
General description
M-CSF (colony stimulating factor 1) is a pleiotropic macrophage growth factor. It has a signal peptide, a 149-amino acid receptor-binding domain, a variable spacer region and a transmembrane region with a cytoplasmic tail. The human M-CSF receptor is a 972-amino acid glycosylated protein which consist of an extracellular region made of five immunoglobulin-like domains (D1–D5), a transmembrane region and an intracellular autocatalytic kinase domain. This gene is mapped to human chromosome p13-p21.
The Human MCSF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MCSF in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human MCSF
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
常规特殊物品
含少量动物源组分生物产品
此项目有
Combinatorial and computational approaches to identify interactions of macrophage colony-stimulating factor (M-CSF) and its receptor c-FMS.
Rosenfeld L, et al.
The Journal of Biological Chemistry, 290(43), 26180-26193 (2015)
Reassignment of the human CSF1 gene to chromosome 1p13-p21.
Morris SW, et al.
Blood, 78(8), 2013-2020 (1991)
Teresa Di Desidero et al.
Pharmacological research, 158, 104920-104920 (2020-05-29)
Anaplastic thyroid cancer (ATC) is a rare neoplasia with a poor prognosis. Proliferation and apoptosis assays were performed on ATC cell lines (8305C, 8505C) exposed to vinorelbine, lenvatinib, as well as to concomitant combinations. ABCB1, ABCG2 and CSF-1 mRNA expression
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