种属反应性
human, rat, mouse
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
enzyme immunoassay: suitable
输入
sample type cell lysate
sample type plasma
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.17 pg/mL
standard curve range: 0.1–1000 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... GCG(2641)
一般描述
GLP-1 酶联免疫分析 (EIA) 试剂盒是基于竞争性酶联免疫分析原理的体外定量检测 GLP-1 肽的方法。
免疫原
胰高血糖素样肽 1 (GLP-1)，合成肽
应用
仅供研究使用。不用于诊断操作。
生化/生理作用
胰高血糖素样肽 I (GLP1) 通过诱导胰岛素分泌和抑制胰高血糖素的分泌来控制葡萄糖的代谢。对印度尼西亚人群的研究显示，这种蛋白水平的降低与 2 类型糖尿病易感性增加有关。这种激素的血浆水平也显示与收缩压和舒张压水平显著相关。
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
常规特殊物品
含少量动物源组分生物产品
此项目有
Maria F Fernandes et al.
International journal of molecular sciences, 23(8) (2022-04-24)
Glucagon-like peptide-1 (GLP-1) potentiates glucose-stimulated insulin secretion (GSIS). While dozens of compounds stimulate GLP-1 secretion, few inhibit. Reduced GLP-1 secretion and impaired GSIS occur in chronic inflammation. Lysophosphatidic acids (LPAs) are bioactive phospholipids elevated in inflammation. The aim of this
Mercaptoacetate blocks fatty acid-induced GLP-1 secretion in male rats by directly antagonizing GPR40 fatty acid receptors
Li AJ, et al.
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 310(8), R724-R732 (2016)
Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient
Beumer J, et al.
Nature Cell Biology, 20(8), 909-909 (2018)
Ai-Jun Li et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 310(8), R724-R732 (2016-01-23)
Mercaptoacetate (MA) is an orexigenic agent reported to block fatty acid (FA) oxidation. Recently, however, we reported evidence from isolated nodose ganglion neurons that MA antagonizes the G protein-coupled long- and medium-chain FA receptor GPR40. GPR40 mediates FA-induced secretion of
Philipp Krisai et al.
Hypertension (Dallas, Tex. : 1979), 65(2), 306-312 (2014-12-03)
Hypertension and diabetes mellitus are highly correlated, but the underlying mechanisms are only partly understood. Therefore, the aim of our study was to investigate the relationships between plasma levels of glucagon-like peptide-1, a key factor in the regulation of glucose
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