产品名称
GLP-1 EIA 试剂盒, for serum, plasma, culture supernatant and cell lysates
species reactivity
human, rat, mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
enzyme immunoassay: suitable
input
sample type cell lysate
sample type plasma
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.17 pg/mL
standard curve range: 0.1–1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GCG(2641)
Application
仅供研究使用。不用于诊断操作。
Biochem/physiol Actions
胰高血糖素样肽 I (GLP1) 通过诱导胰岛素分泌和抑制胰高血糖素的分泌来控制葡萄糖的代谢。对印度尼西亚人群的研究显示，这种蛋白水平的降低与 2 类型糖尿病易感性增加有关。这种激素的血浆水平也显示与收缩压和舒张压水平显著相关。
General description
GLP-1 酶联免疫分析 (EIA) 试剂盒是基于竞争性酶联免疫分析原理的体外定量检测 GLP-1 肽的方法。
Immunogen
胰高血糖素样肽 1 (GLP-1)，合成肽
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
常规特殊物品
含少量动物源组分生物产品
此项目有
Mercaptoacetate blocks fatty acid-induced GLP-1 secretion in male rats by directly antagonizing GPR40 fatty acid receptors
Li AJ, et al.
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 310(8), R724-R732 (2016)
Maria F Fernandes et al.
International journal of molecular sciences, 23(8) (2022-04-24)
Glucagon-like peptide-1 (GLP-1) potentiates glucose-stimulated insulin secretion (GSIS). While dozens of compounds stimulate GLP-1 secretion, few inhibit. Reduced GLP-1 secretion and impaired GSIS occur in chronic inflammation. Lysophosphatidic acids (LPAs) are bioactive phospholipids elevated in inflammation. The aim of this
Jennifer O Adeghate et al.
Cells, 10(8) (2021-08-28)
The effects of early (5-day) onset of diabetes mellitus (DM) on retina ultrastructure and cellular bioenergetics were examined. The retinas of streptozotocin-induced diabetic rats were compared to those of non-diabetic rats using light and transmission electron microscopy. Tissue localization of
Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient
Beumer J, et al.
Nature Cell Biology, 20(8), 909-909 (2018)
Ai-Jun Li et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 310(8), R724-R732 (2016-01-23)
Mercaptoacetate (MA) is an orexigenic agent reported to block fatty acid (FA) oxidation. Recently, however, we reported evidence from isolated nodose ganglion neurons that MA antagonizes the G protein-coupled long- and medium-chain FA receptor GPR40. GPR40 mediates FA-induced secretion of
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