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Merck
CN

RAB0259

Human IL-15 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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UNSPSC代码:
41116158
NACRES:
NA.32
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种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable
capture ELISA: suitable

输入

sample type urine
sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3 pg/mL
standard curve range: 3.3-800 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... IL15(3600)

一般描述

Interleukin-15 (IL-15) is a four α-helical bundle cytokine expressed in the immune system as well as in the skeletal muscles. The IL-15 gene is mapped to human chromosome 4q31.21.
The Human IL-15 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-15 in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human IL-15

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

生化/生理作用

Interleukin-15 (IL-15) is an immunomodulatory cytokine, that plays a key role in the cluster of differentiation CD8+ T cell memory.. It plays a crucial role in the healing of chronic wounds. IL -15 has been implicated in the pathogenesis of autoimmune diseases.

其他说明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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产品编号
说明
化学品安全说明书

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

法规信息

常规特殊物品
低风险生物材料
易制毒化学品(3类)
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Wei Fang et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 143(3), 335-343 (2006-02-04)
Interleukin-15 (IL-15) plays an important role in adaptive immune systems in vertebrates with similar bioactivities to interleukin-2 (IL-2). Here we report molecular cloning, sequence analysis and distribution of an IL-15 homologue from a pufferfish (Tetraodon nigroviridis). It is located within
A M Jones et al.
International journal of molecular medicine, 38(3), 679-686 (2016-07-28)
Chronic wounds represent a significant burden to health services and are associated with patient morbidity. Novel methods to diagnose and/or treat problematic wounds are needed. Interleukin (IL)-15 is a cytokine involved in a number of biological processes and disease states such
Krzysztof Ficek et al.
Frontiers in physiology, 10, 876-876 (2019-07-25)
Based on the important role of interleukin-15 (IL-15) in human metabolism and, in consequence, in body composition modulation, we examined whether rs1589241 and rs1057972 polymorphisms, analyzed individually or in combination, would influence the effects of a training program. Accordingly, we
Thomas A Waldmann
Arthritis research & therapy, 6(4), 174-177 (2004-07-01)
Interleukin (IL)-15 is a dangerous inflammatory cytokine that induces tumor-necrosis factor-alpha, IL-1beta and inflammatory chemokines. It inhibits self-tolerance mediated by IL-2 mediated activation-induced cell death and facilitates maintenance of CD8+ memory T-cell survival including that of self-directed memory cells. Disordered
Pierfrancesco Marra et al.
Cancer research, 74(17), 4908-4921 (2014-07-02)
Despite its aggressive nature, triple-negative breast cancer (TNBC) often exhibits leucocyte infiltrations that correlate with favorable prognosis. In this study, we offer an explanation for this apparent conundrum by defining TNBC cell subsets that overexpress the IL15 immune receptor IL15RA.

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