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Merck
CN

RAB0273

人 IL-1 β ELISA 试剂盒

for serum, plasma, cell culture supernatant and urine

别名:

Il-1 beta, Interleukin-1 beta

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关于此项目

NACRES:
NA.84
UNSPSC Code:
41116158
Gene information:
human ... IL1B(3553)
Input:
sample type urine
sample type serum
sample type plasma
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type urine
sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.3 pg/mL
standard curve range: 0.48-100 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL1B(3553)

General description

人IL-1 β ELISA(酶联免疫吸附测定)试剂盒采用体外酶联免疫吸附测定法,定量测定人血清、血浆、细胞培养物上清液和尿液中的IL-1 β含量。

Immunogen

重组人IL-1β

Application

仅供研究使用。不可用于诊断操作。
人 IL-1 β ELISA试剂盒已被用于测定细胞培养上清液中白细胞介素1β (IL-1 β)的浓度。

Biochem/physiol Actions

白细胞介素1β (IL-1 β)是一种促炎细胞因子,其可诱导多种急性和慢性炎症。因此,IL1B被认为是与纤维化和组织重塑相关的疾病的潜在治疗靶标。 IL-1β 蛋白会增加内源性92kDa明胶酶(基质金属蛋白酶9(MMP-9))和MMP组织抑制剂(TIMP-1)的产生。 滑液中IL-1β 浓度的升高会促进滑膜炎的发病,以及颞下颌关节软骨组织和骨的退行性变化。 IL-1β 可将中性粒细胞和巨噬细胞带到感染部位。 IL-1β 基因突变与Henoch-Schönlein紫癜(HSP)的肾脏表现和肾脏后遗症有关。

Other Notes

本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

存储类别

10 - Combustible liquids

法规信息

低风险生物材料
常规特殊物品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Proinflammatory cytokines detectable in synovial fluids from patients with temporomandibular disorders.
Takahashi T
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 85(2), 135-141 (1998)
Jie Liu et al.
The Journal of international medical research, 49(3), 300060521996564-300060521996564 (2021-03-27)
Porphyromonas gingivalis (Pg) plays a critical role in the occurrence and development of atherosclerosis. Lipopolysaccharide from Pg (Pg-LPS) could lead to pyroptosis of vascular smooth muscle cells (VSMCs) and induce instability of atherosclerotic plaque. Therefore, pyroptosis of VSMCs could promote
Strain- and host species-specific inflammasome activation, IL-1? release, and cell death in macrophages infected with uropathogenic Escherichia coli.
Schaale K
Mucosal Immunology, 9(1), 124-136 (2016)
Differential regulation of monocyte matrix metalloproteinase and TIMP-1 production by TNF-alpha, granulocyte-macrophage CSF, and IL-1 beta through prostaglandin-dependent and -independent mechanisms.
Zhang Y
Journal of Immunology, 161(6), 3071-3076 (1998)
Zhao Gao et al.
BMC ophthalmology, 20(1), 134-134 (2020-04-08)
Inflammation of RPE cells led to different kinds of eye diseases and affected the normal function of the retina. Furthermore, higher levels of ROCK1 and ROCK2 induced injury of endothelial cells and many inflammatory diseases of the eyes. Ripasudil, which

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货号GTIN
RAB0273-1KT04061834961192

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