产品名称
马白介素-1受体拮抗剂/ IL-1F3 ELISA试剂盒, for serum, plasma and cell culture supernatant
species reactivity
equine
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 10 pg/mL
standard curve range: 12.29-3000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
equine ... IL1RN(100034236)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Interleukin-1 receptor antagonist (IL-1RA) inhibits the activity of IL-1α and IL-1β by competitively binding to their type I and type II receptors. IL-1RA plays a vital role in inhibition of acute pro-inflammatory response and forbidding chronic inflammation from damaging healthy tissues. Abnormal expression of IL-1RA leads to development of inflammatory or autoimmune related diseases. Allelic polymorphism of IL-1Rα leads to inflammatory bowel disease (IBD). Therapeutically, IL-1Rα may help in the treatment of sepsis, rheumatoid arthritis, asthma. Overexpression of IL-1Rα is observed in serum of psoriatic arthritis (PsA) patients.
General description
The Equine IL-1ra (interleukin 1 receptor antagonist) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of equine IL-1ra in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Equine IL-1 Receptor Antagonist
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
A novel association between IL1-Ra (receptor antagonist) gene polymorphism and T1DM in Al-Madina Al-Mounawra.
Ali R a, et al.
European Review for Medical and Pharmacological Sciences, 19(19), 3701-3708 (2015)
Allelic polymorphism in IL-1 beta and IL-1 receptor antagonist (IL-1Ra) genes in inflammatory bowel disease.
Bioque G, et al.
Clinical and Experimental Immunology, 102(2), 379-383 (1995)
Serum levels of IL-10, IL-6, IL-1ra, and sIL-2R in patients with psoriatic arthritis.
Elkayam O, et al.
Rheumatology International, 19(3), 101-105 (2000)
Expression of interleukin-1 beta (IL-1beta) and interleukin-1 receptor antagonist (IL-1ra) on asthmatic bronchial epithelium.
Sousa A R, et al.
American Journal of Respiratory and Critical Care Medicine, 154(4 Pt 1), 1061-1066 (1996)
Relationship of plasma leptin to plasma cytokines and human survivalin sepsis and septic shock.
Arnalich F, et al.
The Journal of Infectious Diseases, 180(3), 908-911 (1999)
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Instructions
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