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Merck
CN

RAB0320

人 IL-8/CXCL8 ELISA 试剂盒

for cell and tissue lysates

别名:

C-X-C motif chemokine 8, Granulocyte chemotactic protein 1, IL-8, Interleukin-8, Monocyte-derived neutrophil chemotactic factor, Monocyte-derived neutrophil-activating peptide, Neutrophil-activating protein 1, T-cell chemotactic factor

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关于此项目

NACRES:
NA.32
UNSPSC Code:
41116158
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产品名称

人 IL-8/CXCL8 ELISA 试剂盒, for cell and tissue lysates

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 0.8-600 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL8(3576)

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human IL-8/CXCL8 ELISA Kit has been used to determine serum concentrations of interleukin-8.

General description

The Human IL-8 ELISA (enzyme-linkedimmunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human interleukin-8 (IL-8) cell lysate and tissue lysate. Elevated expression of the gene is observed in a number of cancers including chronic spontaneous urticaria and breast cancer, thus serves as a prognostic marker for the same. IL-8 regulates the metastasis and angiogenesis processes during cancer development.Itis responsible for epithelial-mesenchymal transition which plays an important role in providing cancer cells the mobility to invade other neighbouring cells, thereby contributing to metastasis.

Immunogen

Recombinant Human IL-8

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

存储类别

8A - Combustible corrosive hazardous materials

法规信息

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分析证书(COA)

Lot/Batch Number

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Elevated plasma il-8 concentration is related to severity of systemic inflammation in chronic spontaneous urticaria.
Kasperska ZA, et al.
Journal of Biological Regulators and Homeostatic Agents, 31(4), 957-961 null
Aqueous seed extract of Hunteria umbellata (K. Schum.) Hallier f.(Apocynaceae) palliates hyperglycemia, insulin resistance, dyslipidemia, inflammation and oxidative stress in high-fructose diet-induced metabolic syndrome in rats
Ajiboye TO, et al.
Journal of Ethnopharmacology, 198, 184-193 (2017)
Dioscoreophyllum cumminsii (Stapf) Diels leaves halt high-fructose induced metabolic syndrome: Hyperglycemia, insulin resistance, inflammation and oxidative stress
Ajiboye TO, et al.
Journal of Ethnopharmacology, 192, 471-479 (2016)
Sohlh2 suppresses epithelial to mesenchymal transition in breast cancer via downregulation of IL-8.
Ji S, et al.
Oncotarget, 7(31), 49411-49411 (2016)
Jin-Sung Chung et al.
The Journal of investigative dermatology, 134(11), 2784-2794 (2014-06-18)
A major barrier to successful cancer immunotherapy is the tumor's ability to induce T-cell tolerance by exploiting host regulatory mechanisms. Having discovered the DC-HIL receptor, which inhibits T-cell responses by binding to syndecan-4 on effector T cells, we posited the

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