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Merck
CN

RAB0402

Human Platelet Factor-4 / CXCL4 ELISA Kit

for serum, plasma, cell culture supernatant and urine

别名:

C-X-C motif chemokine 4, Oncostatin-A, PF-4, Platelet factor 4, PF4

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关于此项目

NACRES:
NA.32
UNSPSC Code:
41116158
eCl@ss:
32160701
Gene information:
human ... PF4(5196)
Input:
sample type serum
sample type plasma
sample type urine
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type serum
sample type plasma
sample type urine
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 20.58-15000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... PF4(5196)

General description

The Human PF-4 (Platelet Factor-4) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human PF-4 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human PF4

Application

For research use only. Not for use in diagnostic procedures.
Human Platelet Factor-4 (PF4)/ CXCL4 (chemokine (C-X-C motif) ligand 4) ELISA Kit has been used to measure PF-4 / CXCL4 serum level in chronic myelomonocytic leukemia (CMML) patients.
Human Platelet Factor-4 / CXCL4 ELISA Kit has also been used in the measurement of platelet factor-4 in serum samples of prostate cancer and pseudoxanthoma elasticum patients.

Biochem/physiol Actions

Platelet factor-4 (PF-4) or chemokine (C-X-C motif) ligand 4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. This protein associates with heparin and neutralizes it. It also neutralizes various other negatively charged proteoglycans. PF-4 / CXCL4 is implicated in cancer development. PF-4 regulates the activity of proangiogenic growth factors. PF-4 / CXCL4 function as a biomarker for systemic sclerosis and early tumor growth. PF-4 / CXCL4 is associated with various pathological conditions such as atherosclerosis, liver fibrosis and inflammation.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.


象形图

Health hazard

警示词

Danger

危险代码

预防性声明

Hazard Classifications

Resp. Sens. 1

存储类别

10 - Combustible liquids



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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