species reactivity
rat, human, mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, enzyme immunoassay: suitable
input
sample type plasma
sample type cell lysate
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.27 pg/mL
standard curve range: 1-1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... PTH(5741)
General description
The PTH Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting PTH peptide based on the principle of Competitive Enzyme Immunoassay.
Immunogen
Parathyroid Hormone (PTH), synthetic peptide
Application
PTH / arathyroid hormone EIA kit has been used to determine parathyroid hormone (PTH) levels in human embryonic kidney (HEK293) cells.
Biochem/physiol Actions
Parathyroid hormone (PTH) plays a vital role in regulation calcium homeostasis. It increases bone mass in animals and humans by inhibiting osteoblast apoptosis. PTH has potential applications in preventing fractures in postmenopausal women with osteoporosis. Irregular diurnal patterns of PTH leads to sustained mild hypercalcemia in non dialyzed chronic kidney disease (CKD) patients. PTH, along with other heart failure biomarkers play a vital role in measuring disease severity and prognosis of heart failure with preserved ejection fraction (HFpEF). Variation in PTH leads to osteoporosis in asymptomatic hyperparathyroidism (HPT).
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
Parathyroid hormone is associated with heart failure with preserved ejection fraction.
Bezgin T
Bratislavske lekarske Listy null
Abnormal Diurnal Patterns of Parathyroid Hormone are Associated with Sustained Mild Hypercalcemia in Non-Dialyzed Chronic Kidney Disease.
Yamato M
Clinical Laboratory null
Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone.
Jilka R L
The Journal of Clinical Investigation null
Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.
Neer RM
The New England Journal of Medicine null
Parathyroid Hormone Polymorphism RS6254 is Associated with the Development and Severity of Osteoporosis in Asymptomatic but not Normocalcemic Hyperthyroidism.
Diaz-Soto G
Hormone and Metabolic Research null
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