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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... SELP(6403)
Input:
sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 0.041-30 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... SELP(6403)
General description
The Human P-Selectin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human P-Selectin in serum, plasma, cell culture supernatants and urine.P-selectin, also known as cluster of differentiation 62 (CD62) or granule membrane protein 140 (GMP-140), is a Ca2+-dependent lectin. It is expressed within alpha-granules of platelets and the Weibel-Palade bodies of endothelial cells.
Immunogen
Recombinant Human P-Selectin
Application
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human P-Selectin ELISA (Enzyme-Linked Immunosorbent Assay) kit has been used in ELISA to quantify P-selectin levels in platelet lysates.
For research use only. Not for use in diagnostic procedures.
Human P-Selectin ELISA (Enzyme-Linked Immunosorbent Assay) kit has been used in ELISA to quantify P-selectin levels in platelet lysates.
For research use only. Not for use in diagnostic procedures.
Biochem/physiol Actions
P-selectin serves as an adhesion molecule and plays an important role in leukocyte rolling and attachment. In addition, it also acts a receptor for myeloid cells by associating with sialylated, fucosylated lactosaminoglycans. Overexpression of P-selectin has been observed in apparently healthy women at risk for future vascular events.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
Effects of selenium in the MAPK signaling cascade.
Rashtchizadeh N, et al.
Journal of cardiovascular and thoracic research, 7(3), 107-107 (2015)
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.
Moore K L, et al.
The Journal of Cell Biology, 118(2), 445-456 (1992)
Soluble P-selectin and the risk of future cardiovascular events.
Ridker P M, et al.
Circulation, 103(4), 491-495 (2001)
Nadereh Rashtchizadeh et al.
Journal of cardiovascular and thoracic research, 7(3), 107-112 (2015-10-03)
This study aimed to discover by which mechanism selenium (Se) suppresses stimulated platelets stimulation in oxidative stress underlying diseases. Human platelets pretreated with Se and stimulated by Cu(2+)-oxidized low density of lipoprotein (OxLDL) or thrombin before assessment of P-selectin and
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