RAB0500
Human p53 ELISA Kit
for serum, plasma, cell culture supernatant and urine
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... TP53(7157)
Input:
sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type plasma
sample type urine
sample type serum
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.3 ng/mL
standard curve range: 0.328-80 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TP53(7157)
General description
Cellular tumor antigen p53 is a tumor-suppressor protein that comprises transactivation at N-terminus, central sequence-specific DNA-binding domain, and regulatory domain at C-terminus. It plays a key role in autophagy regulation. It inhibits tumors and acts as a cellular stress sensor especially during nutrient deprivation, hypoxia, and ribosome dysfunction. The Human p-53 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human p-53 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human p53
Application
Human p53 ELISA Kit has been used for quantifying p53 using enzyme-linked immunosorbent assay (ELISA) in human myeloma RPMI-8226 cells, human colorectal cancer HCT-116 cells, human breast cancer MCF-7 cells and human leukemiaHL-60 cells.
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
10 - Combustible liquids
法规信息
常规特殊物品
低风险生物材料
此项目有
Evaluation of roscovitine anticancer agent as a reference compound for cancer and apoptosis studies
Taha H, et al.
JIMD Reports null
Mohammed K Abd Elhameid et al.
Chemical & pharmaceutical bulletin, 66(10), 939-952 (2018-08-17)
A new series of pyridine and pyrimidine derivatives is designed and synthesized as potential antitumor molecules. The tested compounds show promising in vitro cytotoxic activity against HL-60 cell line as eight compounds: 4, 6, 11, 13, 14, 15, 18 and
p53 at a glance.
Colleen A Brady et al.
Journal of cell science, 123(Pt 15), 2527-2532 (2010-10-14)
Mohammed K Abd El Hameid et al.
Bioorganic chemistry, 86, 609-623 (2019-02-27)
The work representing the design and the cytotoxic screening of synthetic small molecules (SSMs) such as carbonitriles 3a-c, carboximidamides 4a-c, and oxadiazoles 5-19 as antitumor molecules. Molecules 4c, 9, 12, and 14 show promising cytotoxicity profiles against two cell lines
Karen H Vousden et al.
Nature reviews. Molecular cell biology, 8(4), 275-283 (2007-03-24)
As a component of the response to acute stress, p53 has a well established role in protecting against cancer development. However, it is now becoming clear that p53 can have a much broader role and can contribute to the development
相关内容
Instructions
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| RAB0500-1KT | 04061834963035 |
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持