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Merck
CN

RAB0510

小鼠VEGF ELISA试剂盒

for cell and tissue lysates

别名:

VEGF-A

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关于此项目

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Vegfa(22339)
Input:
sample type cell lysate
sample type tissue lysate
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 4.1-1000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Vegfa(22339)

General description

The Mouse VEGF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse VEGF cell lysate and tissue lysate.

Immunogen

Recombinant Mouse VEGF-A

Application

Mouse VEGF ELISA Kit has been used to determine the concentration of VEGF expression in samples using ELISA.
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Vascular endothelial growth factor (VEGF) is a critical factor in regulating angiogenesis in both physiological and pathological conditions. Transforming growth factor-α (TGF-α), TGF-β and platelet derived growth factor can potentially activate VEGF activity. VEGF mediates its activity through tyrosine kinase receptors, vascular endothelial growth factor receptor-1 (VEGFR-1) and VEGFR-2. VEGF produced by tumour cells and macrophages, plays a key role in cancer development by promoting endothelial cells proliferation and increasing vascular permeability. Enhanced expression of VEGF plays a key role in urologic neoplasm like bladder cancer, renal cell carcinoma, and cervical cancer. Polymorphism in VEGF gene increases the disease susceptibility. Blocking of VEGF mediated signalling pathway is a potential therapeutic strategy for cancer patients.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.


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产品编号
说明
化学品安全说明书 & 价格

  • ELISA 5X Sample Diluent Buffer (Item D2)
    化学品安全说明书

  • ELISA 5X Assay/Sample Diluent Buffer E (Item E2)
    化学品安全说明书

  • 2X Cell Lysis Buffer (Item J)
    化学品安全说明书

  • ELISA Stop Solution (Item I)
    化学品安全说明书

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    化学品安全说明书

  • 20X Wash Buffer (Item B)
    化学品安全说明书

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

存储类别

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容


The crucial role of blood VEGF kinetics in patients with locally advanced esophageal squamous cell carcinoma receiving curative concurrent chemoradiotherapy
Chen YH, et al.
BMC Cancer, 18(1), 837-837 (2018)
Parthenolide inhibits tumor-promoting effects of nicotine in lung cancer by inducing P53-dependent apoptosis and inhibiting VEGF expression
Talib WH, et al.
Biomedicine and Pharmacotherapy, 107, 1488-1495 (2018)
Combination of metformin and curcumin targets breast cancer in mice by angiogenesis inhibition, immune system modulation and induction of p53 independent apoptosis
Falah RR, et al.
Therapeutic Advances in Medical Oncology, 9(4), 235-252 (2017)



全球贸易项目编号

货号GTIN
RAB0510-1KT04061834963127