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Merck
CN

RAB0539

人AHSG /α-2-HS-糖蛋白ELISA试剂盒

for serum, plasma and cell culture supernatants

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关于此项目

NACRES:
NA.32
UNSPSC Code:
41116158
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产品名称

人AHSG /α-2-HS-糖蛋白ELISA试剂盒, for serum, plasma and cell culture supernatants

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum
sample type cell culture supernatant(s)

assay range

inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.2 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... AHSG(197)

Application

请参考Protocol了解详情。

Biochem/physiol Actions

α 2-HS glycoprotein (AHSG), also referred to as fetuin-A, is a major serum protein component that exerts various calcium-dependent physiological activities and can mediate growth signaling in certain tumor cells. It can also act as a natural antagonist against specific TGF-β (transforming growth factor β) and BMP (bone morphogenetic protein) signaling proteins. High levels of fetuin-A in the serum is associated with mild osteogenesis imperfecta. On the other hand, reduced levels are seen in Paget′s disease. It is predicted as a potential biomarker for the early diagnosis of hypopharyngeal squamous cell carcinoma.

General description

This ELISA antibody pair detects human Alpha-2-HS-glycoprotein.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

存储类别

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Proteomic identification of alpha-2-HS-glycoprotein as a plasma biomarker of hypopharyngeal squamous cell carcinoma.
Tian WD, et al.
International Journal of Clinical and Experimental Pathology, 8(8), 9021-9021 (2015)
Claas Jasper Steffen et al.
Archives of orthopaedic and trauma surgery, 140(10), 1359-1366 (2019-12-21)
In the elderly, osteoporotic fractures of the femur are associated with high morbidity and mortality. At the time of hospitalization and during pre-operative care identification of patients at risk for poor outcome despite an otherwise good clinical condition is challenging.
Association of alpha2-HS glycoprotein (AHSG, fetuin-A) polymorphism with AHSG and phosphate serum levels.
Osawa M, et al.
Human Genetics, 116(3), 146-151 (2005)
Margarida Sarmento-Dias et al.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 37(4), 451-457 (2017-01-18)
Fluid overload (FO) is frequently present in peritoneal dialysis (PD) patients and is associated with markers of malnutrition, inflammation, and atherosclerosis/calcification (MIAC) syndrome. We examined the relationships in stable PD patients between phase angle (PhA) and the spectrum of uremic
Abdullahi Mudi et al.
Clinical nephrology, 92(5), 250-257 (2019-08-27)
Increased carotid intima media thickness (cIMT) is one of the early changes seen in chronic kidney disease (CKD) associated cardiovascular disease. This study aimed to determine cIMT measurements and its association with cardiovascular risk factors, including fibroblast growth factor-23 (FGF-23)

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