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Merck
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RAB0540

人FGF19/成纤维细胞生长因子19 ELISA试剂盒

for serum, plasma, cell culture supernatants and urine

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关于此项目

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... FGF19(9965)
Input:
sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
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产品名称

人FGF19/成纤维细胞生长因子19 ELISA试剂盒, for serum, plasma, cell culture supernatants and urine

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 30 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... FGF19(9965)

Application

仅供研究使用。不可用于诊断操作。
请参考附带的一般ELISA试剂盒操作程序(夹心、竞争性 & 间接ELISA)

Biochem/physiol Actions

成纤维细胞生长因子(FGF)19通过激活FGF受体4来控制靶器官中的胆汁酸、脂肪酸、葡萄糖和磷酸盐代谢。FGF19通过激活胰岛素非依赖性内分泌途径调节肝蛋白和糖原代谢。在糖尿病小鼠中,FGF19降低了血清葡萄糖和甘油三酸酯的水平。该基因的过度表达导致肝细胞癌(HCC)的发展。

General description

该ELISA抗体对可检测人成纤维细胞生长因子19。

Other Notes

本产品提供样本检验报告。
请在批号对应的文本框中输入样品 一词。

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

存储类别

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

含少量动物源组分生物产品
常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Helene Johansson et al.
Frontiers in endocrinology, 11, 554922-554922 (2021-03-12)
Bile acids (BAs) are detergents essential for intestinal absorption of lipids. Disruption of BA homeostasis can lead to severe liver damage. BA metabolism is therefore under strict regulation by sophisticated feedback mechanisms. The hormone-like protein Fibroblast growth factor 19 (FGF19)
Weihua Chen et al.
Clinical reviews in allergy & immunology, 58(1), 25-38 (2019-03-23)
Accumulation of bile acids (BAs) contributes significantly to the pathogenesis of primary biliary cholangitis (PBC). Here, we sought to systematically characterize the serum and fecal BA profiles and the linkage between BAs and gut microbiota in PBC. The serum and
Aze Wilson et al.
Scientific reports, 10(1), 1866-1866 (2020-02-07)
Bile acids are endogenous ligands of nuclear receptors pregnane X (PXR) and farnesoid X (FXR). PXR and FXR regulate pathways that are impaired in inflammatory bowel disease (IBD). Decreases in PXR and FXR activity are documented in IBD; however reasons
Kai Wang et al.
Cell reports, 26(1), 222-235 (2019-01-04)
We demonstrated the metabolic benefits of Parabacteroides distasonis (PD) on decreasing weight gain, hyperglycemia, and hepatic steatosis in ob/ob and high-fat diet (HFD)-fed mice. Treatment with live P. distasonis (LPD) dramatically altered the bile acid profile with elevated lithocholic acid (LCA)
Samer Al-Dury et al.
Scientific reports, 8(1), 6658-6658 (2018-04-29)
Pruritus is a common complication of cholestatic liver diseases. Inhibition of the ileal bile acid transporter (IBAT/ASBT) may emerge as treatment option. Our aim was to assess tolerability and effect on pruritus of the selective IBAT inhibitor A4250 in patients

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