种属反应性
mouse
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
输入
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.1 ng/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Esm1(71690)
一般描述
This ELISA antibody pair detects mouse Endothelial Cell-specific Molecule 1. Endothelial cell-specific molecule 1 (ESM1) is a secreted dermatan sulfate proteoglycan. This cysteine-rich protein is expressed in kidney glomeruli, specifically in renal epithelia and endothelial cells. Proangiogenic factors and cytokines modulate its activity.
应用
请参考Protocol了解详情。
生化/生理作用
Endothelial cell-specific molecule 1 (ESM1) may have a role in inflammation and angiogenesis. It has been linked to tumor growth. ESM1 stimulates vascular sprouting, growth, differentiation, migration and adhesion of cells.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1).
Cong R
Biochemical and Biophysical Research Communications (2006)
ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma.
Chen C
Oncotarget (2016)
The non glycanated endocan polypeptide slows tumor growth by inducing stromal inflammatory reaction.
Yassine H
Oncotarget (2015)
Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy.
Zheng X
PLoS ONE (2017)
Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.
Rocha SF
Circulation Research (2014)
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