产品名称
小鼠Esm1 /内皮细胞特异性分子1 ELISA试剂盒, for serum, plasma and cell culture supernatants
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.1 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Esm1(71690)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Endothelial cell-specific molecule 1 (ESM1) may have a role in inflammation and angiogenesis. It has been linked to tumor growth. ESM1 stimulates vascular sprouting, growth, differentiation, migration and adhesion of cells.
General description
This ELISA antibody pair detects mouse Endothelial Cell-specific Molecule 1. Endothelial cell-specific molecule 1 (ESM1) is a secreted dermatan sulfate proteoglycan. This cysteine-rich protein is expressed in kidney glomeruli, specifically in renal epithelia and endothelial cells. Proangiogenic factors and cytokines modulate its activity.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.
Rocha SF
Circulation Research (2014)
ESM1 mediates NGFR-induced invasion and metastasis in murine oral squamous cell carcinoma.
Chen C
Oncotarget (2016)
The non glycanated endocan polypeptide slows tumor growth by inducing stromal inflammatory reaction.
Yassine H
Oncotarget (2015)
Hhex is a direct repressor of endothelial cell-specific molecule 1 (ESM-1).
Cong R
Biochemical and Biophysical Research Communications (2006)
Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy.
Zheng X
PLoS ONE (2017)
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