RAB0610
人 APOB/载脂蛋白 B-100 ELISA 试剂盒
别名:
Apo B-100, Apolipoprotein B-100
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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... APOB(338)
Input:
sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type plasma
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.5 ng/mL
standard curve range: 2.458-600 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... APOB(338)
General description
The ApoB ELISA kit provides for the Quantitative measurement of ApoB-100 in Cell Culture Supernatants, Plasma and Serum.
The APOB (apolipoprotein B) gene is mapped to human chromosome 2p24.1. Apob protein is an amphipathic protein that exists as α- helices and β-sheets. Apob is present in the major lipoproteins : chylomicrons, low density lipoproteins and very low density lipoprotein.
The APOB (apolipoprotein B) gene is mapped to human chromosome 2p24.1. Apob protein is an amphipathic protein that exists as α- helices and β-sheets. Apob is present in the major lipoproteins : chylomicrons, low density lipoproteins and very low density lipoprotein.
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Apob (apolipoprotein B) functions in the low-density lipoprotein cholesterol segregation. Increased APOB gene expression is observed in non-alcoholic fatty liver disease and contributes to its pathogenesis. Reduced Apob protein is indicated in familial hypobetalipoproteinemia.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Serum apoB levels independently predict the development of non-alcoholic fatty liver disease: A 7-year prospective study.
Wang J, et al.
Liver International : Official Journal of the International Association For the Study of the Liver, 37(8), 1202-1208 (2017)
Lipoproteomics: using mass spectrometry-based proteomics to explore the assembly, structure, and function of lipoproteins.
Hoofnagle A N and Heinecke J W
Journal of Lipid Research, 50(10), 1967-1975 (2009)
Identification of novel APOB mutations by targeted next-generation sequencing for the molecular diagnosis of familial hypobetalipoproteinemia.
Rimbert A, et al.
Atherosclerosis, 250, 52-56 (2016)
Alejandro Escobedo et al.
Nutrients, 13(11) (2021-11-28)
Snack alternatives based on common beans (Phaseolus vulgaris L.) have been developed to promote pulse consumption. The purpose of this study was to evaluate the chemical composition, sensory acceptance and the effect of common bean baked snack (CBBS) consumption on
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
Chasman DI, et al.
PLoS Genetics, 5(11), e1000730-e1000730 (2009)
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