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Merck
CN

RAB0634

人TNNI3 /肌钙蛋白I,心肌ELISA试剂盒

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关于此项目

NACRES:
NA.32
UNSPSC Code:
41116158
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 100 pg/mL
standard curve range: 125-8000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TNNI3(7137)

Application

仅供研究使用。不可用于诊断操作。
请参考附带的一般ELISA试剂盒操作程序(夹心、竞争性 & 间接ELISA)

Biochem/physiol Actions

心肌肌钙蛋白I(cTnI)与扩张型心肌病相关,病理表现为左心室扩张,收缩能力下降。cTnI与心肌肌钙蛋白T和C共同组成肌钙蛋白复合体。cTnI可抑制肌动蛋白-肌球蛋白的相互作用。它通过影响Ca2+敏感度参与肌节激活。cTnI也可作为心肌损伤标志物。

General description

人心肌肌钙蛋白(TNNI3)ELISA试剂盒用于定量测定细胞培养上清、血浆和血清中的肌钙蛋白I。

Other Notes

本产品提供样本检验报告。
请在批号对应的文本框中输入样品 一词。

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

存储类别

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sandra Funcke et al.
Biomolecules, 10(9) (2020-09-17)
Intermittent hypoxia and various pharmacological compounds protect the heart from ischemia reperfusion injury in experimental approaches, but the translation into clinical trials has largely failed. One reason may lie in species differences and the lack of suitable human in vitro
Hongrui Chen et al.
Life sciences, 207, 492-498 (2018-07-03)
The clinical use of doxorubicin (Dox) is limited due to a degenerative irreversible cardiac toxicity, but the precise mechanisms that contribute to this pathological response are not understood. C1q/TNF-related protein 1 (CTRP1), which is a conserved protein of the C1q
Junjie Guo et al.
Shock (Augusta, Ga.), 49(6), 712-720 (2017-08-29)
Chronic kidney disease (CKD) is known to exacerbate myocardial ischemia reperfusion (IR) injury. However, the underlying mechanisms are still not well understood. Despite various strategies for cardioprotection, limited studies have been focused on the prevention of CKD-induced myocardial susceptibility to
Correlation of corrected QT interval with quantitative cardiac troponin-I levels and its prognostic role in Non-ST-elevation myocardial infarction
Rajvanshi S, et al.
International Journal of Cardiology, 240(14), 55-59 (2017)
Genotype-specific pathogenic effects in human dilated cardiomyopathy
Bollen IA, et al.
The Journal of Physiology, 595(14), 4677-4693 (2017)

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