RAB0689
人IL36G /白介素36γELISA试剂盒
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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... IL36G(56300)
Input:
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type cell culture supernatant(s)
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 13 pg/mL
standard curve range: 12.29-3000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL36G(56300)
General description
The IL36G ELISA kit provides for the Quantitative measurement of IL-36 gamma in Cell Culture Supernatants, Plasma and Serum.
Interleukin-36 gamma (IL36G), also known as IL-1F9, is a member of interleukin (IL)-1-like proinflammatory cytokine family. It is encoded by the gene mapped to human chromosome 2q12-q21. IL36G is abundantly expressed in epithelial tissues and numerous myeloid-derived cell types.
Interleukin-36 gamma (IL36G), also known as IL-1F9, is a member of interleukin (IL)-1-like proinflammatory cytokine family. It is encoded by the gene mapped to human chromosome 2q12-q21. IL36G is abundantly expressed in epithelial tissues and numerous myeloid-derived cell types.
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Members of interleukin (IL)-1 family of cytokines play a vital role in regulating immune responses to infectious challenges and sterile insults. IL-36 is implicated in mucosal immunity, such as lung anti-bacterial responses. Interleukin-36 γ (IL36G) participates in inflammation response and differentiation. Overexpression of IL36G has been observed in psoriasis patients. Thus, down regulation IL36G can be considered as an effective method to treat psoriasis.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Participation of interleukin family 1 in the development of inflammatory reaction in the infectious process. 1. General characteristics of the interleukin family 1.
Abaturov AE, et al.
CHILDS HEALTH (2014)
IL-1 family cytokines in cardiovascular disease.
Pfeiler S, et al.
Cytokine (2017)
IL-36γ inhibits differentiation and induces inflammation of keratinocyte via Wnt signaling pathway in psoriasis.
Wang W, et al.
International Journal of Medical Sciences, 14(10), 1002-1002 (2017)
IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and-negative bacterial pneumonia.
Kovach MA, et al.
Mucosal Immunology, 10(5), 1320-1320 (2017)
Jennifer Mildenberger et al.
Autophagy, 13(10), 1664-1678 (2017-08-19)
Inflammation is crucial in the defense against infections but must be tightly controlled to limit detrimental hyperactivation. Our diet influences inflammatory processes and omega-3 polyunsaturated fatty acids (n-3 PUFAs) have known anti-inflammatory effects. The balance of pro- and anti-inflammatory processes
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