RAB0719
人SSSCA1 / Sjoegren综合征/硬皮病自身抗原1 ELISA试剂盒
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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... SSSCA1(10534)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... SSSCA1(10534)
General description
The SSSCA1 (Sjoegren syndrome/scleroderma autoantigen 1) gene codes for a cell cycle inhibitor, also called as p27. The SSSCA1 gene is mapped to human chromosome 11q13.1.
The antibody pair provided in this kit recognizes human SSSCA1.
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Sjoegren Syndrome Autoantigen 1 is an important cyclin-dependent kinase complexes inhibitor and prevents the G1 to S phase transition during cell cycle. It is regulated by ubiquitin-proteasome. The Sjoegren Syndrome Autoantigen 1 gene expression is downregulated in cancer and indicates poor prognosis.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Loss of 3p26. 3 is an independent prognostic factor in patients with oral squamous cell carcinoma.
Uchida K, et al.
Oncology Reports, 26(2), 463-469 (2011)
Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis.
Shen A, et al.
Neurosurgery, 65(1), 153-160 (2009)
Subcellular localization of p27 and prostate cancer recurrence: automated digital microscopy analysis of tissue microarrays.
Ananthanarayanan V, et al.
Human Pathology, 42(6), 873-881 (2011)
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