人SHBG /性激素结合球蛋白ELISA试剂盒

Name: 人SHBG /性激素结合球蛋白ELISA试剂盒
Brand: SIGMA

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About This Item

UNSPSC代码:

41116158

NACRES:

NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable

输入

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.2 pmol/L
standard curve range: 1.229-300 pmol/L

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... SHBG(6462)

一般描述

Serum sex hormone-binding globulin (SHBG) protein is a homodimer with a signal peptide and two laminin G-like domains. SHBG is produced by testis germ cells and released into the bloodstream by the liver. SHBG gene is located on human chromosome 17p13.1.

应用

Human SHBG/Sex Hormone-binding Globulin ELISA Kit has been used to measure serum sex hormone-binding globulin (SHBG) in whole blood samples. It has also been used to quantify SHBG in maternal peripheral and umbilical cord blood.

生化/生理作用

Serum sex hormone-binding globulin (SHBG) can bind and transport sex steroids and aid in modulating their biological active fraction. Direct action of SHBG modulates sex steroid actions in target cells. A low level of SHBG is detected in women with polycystic ovary syndrome (PCOS). The SHBG ELISA kit can be used for the quantitative measurement of sex hormone-binding globulin in cell culture supernatants, plasma and serum.