species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.35 ng/mL
standard curve range: 0.391-25 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TNNT1(7138)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Troponin T plays a vital role in calcium regulation of striated muscle contraction and relaxation. The alternative splicing regulation of troponin T1, slow skeletal type (TNNT1) expression has been implicated in regulation of muscle contractility in physiological and pathophysiological adaptations. Mutation in the gene is associated with the development of Nemaline myopathy.
General description
Troponin T1, slow skeletal type (TNNT1) is encoded by the gene mapped to human chromosome 19q13.4. The encoded protein is composed of 261 amino acids and is expressed specifically in slow skeletal muscle.
Other Notes
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Bergita Ganse et al.
Experimental cell research, 399(2), 112463-112463 (2021-01-02)
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Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells.
Ware C B, et al.
Cell Stem Cell, 4(4), 359-369 (2009)
TNNT1, TNNT2, and TNNT3: Isoform Genes, Regulation, and Structure-Function Relationships.
Wei B and Jin J P
Gene, 582(1), 1-13 (2016)
Rui Tian et al.
Experimental cell research, 357(2), 328-334 (2017-06-08)
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and irreversible lung disease. Studies have shown that epithelial-mesenchymal transition (EMT) plays an important role in the development of IPF. The NLRP3 inflammasome is reported to be activated and play an important
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