种属反应性
mouse
技术
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
运输
wet ice
储存温度
−20°C
一般描述
Immunoglobulin M (IgM) is a highly conserved antibody in vertebrates and shows early expression during the immune response. Peritoneal B cells secrete IgM and it exists as a pentamer. IgM plays a key role in engulfing the apoptotic cells. A reduction in the serum IgM levels leads to an increase in autoimmune response and a higher risk for infections. IgM displays polyreactive and autoreactive functionality. It plays a key role in tissue homeostasis by mediating the clearance of tissue-based molecules. The antibody pair provided in this kit recognizes mouse IgM.
应用
请参考Protocol了解详情。
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Ian J Begeman et al.
PLoS neglected tropical diseases, 11(6), e0005670-e0005670 (2017-06-27)
Congenital toxoplasmosis is a serious but preventable and treatable disease. Gestational screening facilitates early detection and treatment of primary acquisition. Thus, fetal infection can be promptly diagnosed and treated and outcomes can be improved. We tested 180 sera with the
Simon A Reid et al.
BMC public health, 17(1), 671-671 (2017-08-24)
Zoonotic diseases such as leptospirosis occur as a result of the often complex interactions that exist at the human-animal-environment interface. The most obvious consequence of this complexity is the need for the health sector to partner with institutions in other
Lori Broderick et al.
Nature communications, 10(1), 3644-3644 (2019-08-15)
B cell development is a highly regulated process involving multiple differentiation steps, yet many details regarding this pathway remain unknown. Sequencing of patients with B cell-restricted immunodeficiency reveals autosomal dominant mutations in TOP2B. TOP2B encodes a type II topoisomerase, an
A A R Thompson et al.
Science immunology, 2(8) (2017-04-08)
Hypoxia and bacterial infection frequently co-exist, in both acute and chronic clinical settings, and typically result in adverse clinical outcomes. To ameliorate this morbidity, we investigated the interaction between hypoxia and the host response. In the context of acute hypoxia
Lorenzo E Hernández-Castellano et al.
Journal of dairy science, 102(9), 8478-8485 (2019-07-01)
Several physiological and metabolic changes take place in dairy ruminants around parturition (late pregnancy, parturition, and early lactation). Dairy species are genetically selected for their higher milk production compared with non-dairy species. This fact causes a constant stress that impairs
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