species reactivity
mouse
technique(s)
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
shipped in
wet ice
storage temp.
−20°C
General description
Immunoglobulin M (IgM) is a highly conserved antibody in vertebrates and shows early expression during the immune response. Peritoneal B cells secrete IgM and it exists as a pentamer. IgM plays a key role in engulfing the apoptotic cells. A reduction in the serum IgM levels leads to an increase in autoimmune response and a higher risk for infections. IgM displays polyreactive and autoreactive functionality. It plays a key role in tissue homeostasis by mediating the clearance of tissue-based molecules. The antibody pair provided in this kit recognizes mouse IgM.
Application
请参考Protocol了解详情。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Simon A Reid et al.
BMC public health, 17(1), 671-671 (2017-08-24)
Zoonotic diseases such as leptospirosis occur as a result of the often complex interactions that exist at the human-animal-environment interface. The most obvious consequence of this complexity is the need for the health sector to partner with institutions in other
Lori Broderick et al.
Nature communications, 10(1), 3644-3644 (2019-08-15)
B cell development is a highly regulated process involving multiple differentiation steps, yet many details regarding this pathway remain unknown. Sequencing of patients with B cell-restricted immunodeficiency reveals autosomal dominant mutations in TOP2B. TOP2B encodes a type II topoisomerase, an
Stefan Malafa et al.
PLoS neglected tropical diseases, 14(2), e0008034-e0008034 (2020-02-06)
Zika virus has recently spread to South- and Central America, causing congenital birth defects and neurological complications. Many people at risk are flavivirus pre-immune due to prior infections with other flaviviruses (e.g. dengue virus) or flavivirus vaccinations. Since pre-existing cross-reactive
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| RAB0806-1KT | 04061835165834 |