species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Olr1(108078)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Oxidized low-density lipoprotein receptor 1 (OLR1), also referred as Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), acts as a scavenger receptor for oxidized low-density lipoprotein (ox-LDL). It is essential for formation and progression of atherosclerotic plaques. Therefore, mutation in the gene increases the risk of susceptibility to atherosclerotic-related diseases. In addition, genetic variation in the gene leads to myocardial infarction. Serum concentration of OLR1 serves as an efficient biomarker of intracerebral hemorrhage (ICH).
General description
The antibody pair provided in this kit recognizes mouse Oxidized Low-density Lipoprotein Receptor 1.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage
Inoue T, et al.
Journal of Stroke and Cerebrovascular Diseases : The Official Journal of National Stroke Association, 28(2), 490-494 (2019)
Chiyo Nakashima-Nakasuga et al.
International journal of clinical oncology, 25(7), 1308-1317 (2020-04-12)
Colorectal cancer is the third most common cancer worldwide. If biomarkers can be identified in liquid biopsy, diagnosis and treatment can be optimized even when cancerous tissues are not available. The purpose of this study was to identify proteins from
Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction
Tatsuguchi M, et al.
Biochemical and Biophysical Research Communications, 303(1), 247-250 (2003)
LOX-1 and atherosclerotic-related diseases.
Jin P and Cong S
Clinica Chimica Acta; International Journal of Clinical Chemistry, 491, 24-29 (2019)
Akshay Sood et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 51(5), 459-466 (2014-01-23)
Adipose tissue produces adiponectin, an anti-inflammatory protein. High systemic total adiponectin is associated with a low risk for incident asthma but the association with lung adiponectin is not known. Our objective was to evaluate the association between sputum total adiponectin
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