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Merck
CN

RAB1108

Sigma-Aldrich

兔IL-1 β ELISA试剂盒

for cell culture supernatants, plasma, and serum samples

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UNSPSC代码:
41116158
NACRES:
NA.32
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种属反应性

rabbit

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable

输入

sample type serum sample(s)
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/ml

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

rabbit ... IL1B(100008990)

一般描述

This enzyme-linked immunosorbent assay (ELISA) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of a target protein in biological samples, such as serum, plasma, cell culture supernatants, urine and/or cell and tissue lysates.

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化/生理作用

Interleukin 1 beta (IL-1β) is a proinflammatory cytokine, which is implicated in the induction of various acute and chronic inflammation. IL1B is considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. Mutations in IL-1β gene are linked with renal manifestations and renal sequelae in Henoch-Schönlein purpura (HSP).

其他说明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

低风险生物材料
常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Eric G Romanowski et al.
Infection and immunity, 89(8), e0011121-e0011121 (2021-04-07)
In this study, we tested the hypothesis that the conserved bacterial IgaA-family protein, GumB, mediates microbial pathogenesis associated with Serratia marcescens ocular infections through regulation of the Rcs stress response system. The role of the Rcs system and bacterial stress
Interleukin 1 beta (IL1) rs16944 genetic variant as a genetic marker of severe renal manifestations and renal sequelae in Henoch-Schonlein purpura.
Lopez MR, et al.
Clinical and Experimental Rheumatology, S84-S88 (2016)
Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis.
Kolb M
The Journal of Clinical Investigation, 107(12), 1529-1536 (2001)

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