产品名称
兔IL-1 β ELISA试剂盒, for cell culture supernatants, plasma, and serum samples
species reactivity
rabbit
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type serum sample(s)
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
rabbit ... IL1B(100008990)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
Interleukin 1 beta (IL-1β) is a proinflammatory cytokine, which is implicated in the induction of various acute and chronic inflammation. IL1B is considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. Mutations in IL-1β gene are linked with renal manifestations and renal sequelae in Henoch-Schönlein purpura (HSP).
General description
This enzyme-linked immunosorbent assay (ELISA) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of a target protein in biological samples, such as serum, plasma, cell culture supernatants, urine and/or cell and tissue lysates.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Interleukin 1 beta (IL1) rs16944 genetic variant as a genetic marker of severe renal manifestations and renal sequelae in Henoch-Schonlein purpura.
Lopez MR, et al.
Clinical and Experimental Rheumatology, S84-S88 (2016)
Eric G Romanowski et al.
Infection and immunity, 89(8), e0011121-e0011121 (2021-04-07)
In this study, we tested the hypothesis that the conserved bacterial IgaA-family protein, GumB, mediates microbial pathogenesis associated with Serratia marcescens ocular infections through regulation of the Rcs stress response system. The role of the Rcs system and bacterial stress
Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis.
Kolb M
The Journal of Clinical Investigation, 107(12), 1529-1536 (2001)
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