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安全信息

RAB1475

Sigma-Aldrich

人半乳凝素9 ELISA

for serum, plasma and cell culture supernatants

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NACRES:
NA.32

species reactivity

human

包装

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 36 pg/mL
standard curve range: 36.86-9000 pg/mL

detection method

colorimetric

运输

wet ice

储存温度

−20°C

Gene Information

human ... LGALS9(3965)

相关类别

一般描述

Galectin-9 is generally a part of extracellular secretions but is also localized to endothelial cells, T cells and dendritic cells. Galectin-9 is a S-type lectin and its gene is mapped to human chromosome 17q11.2.
This ELISA antibody pair detects Human Galectin-9 (LGALS9)

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化/生理作用

Galectin is a β-galactoside-binding secretory protein, which also has a carbohydrate-recognition domain. Galectin contributes to cancer progression by interacting with oncogenic proteins on the cell surface, such as integrins, fibronectin and laminin. Galectin is also known to suppress immune response in conditions such as melanoma, neuroblastoma and pancreatic carcinoma.

其他说明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

象形图

Corrosion
GHS05

警示用语：

Warning

危险声明

H290

预防措施声明

P234 - P390

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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索取COA

Tim3/galectin-9 alleviates the inflammation of TAO patients via suppressing Akt/NF-kB signaling pathway.
Luo L H, et al.
Biochemical and Biophysical Research Communications, 491(4), 966-972 (2017)
Galectin-9 binds to O-glycans on protein disulfide isomerase.
Schaefer K, et al.
Glycobiology, 27(9), 878-887 (2017)
Elevated Galectin-9 Suppresses Th1 Effector Function and Induces Apoptosis of Activated CD4+ T Cells in Osteoarthritis.
Yang S, et al.
Inflammation, 40(3), 1062-1071 (2017)
Characterization of a de novo sSMC 17 detected in a girl with developmental delay and dysmorphic features.
Stavber L, et al.
Molecular Cytogenetics, 10(1), 10-10 (2017)
Binding of galectin-1 to integrin β1 potentiates drug resistance by promoting survivin expression in breast cancer cells.
KeeSoo N, et al.
Oncotarget, 8(22), 35804-35823 (2017)
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