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Merck
CN

RB354-05

Rabbit Aortic Smooth Muscle Cells: RbAOSMC (Cryovial)

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关于此项目

NACRES:
NA.81
UNSPSC Code:
41106514
eCl@ss:
32040201
Biological source:
rabbit aorta (normal tunica intima and media)
Growth mode:
Adherent
Morphology:
smooth muscle
Relevant disease(s):
cardiovascular diseases
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biological source

rabbit aorta (normal tunica intima and media)

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 44

morphology

smooth muscle

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

cardiovascular diseases

shipped in

dry ice

storage temp.

−196°C

General description

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RbAOSMC from Cell Applications, Inc. were used to demonstrate that anti-restenosis drug probucol inhibition of vascular smooth cell proliferation by enhancing apoptosis and inducing heme oxygenase-1 (Deng, 2004). RbAOSMC were also used to evaluate performance of a novel pH/CO2 sensor system for measuring metabolic activity of cultured cells (Mohri, 2006); and to characterize the receptor pharmacology, antiplatelet activity, and vascular pharmacology of APD791, a novel 5-HT2A receptor antagonist (Adams, 2009).Characterization: positive for smooth muscle cell specific alpha-actin expression.

Application

aortic wall contraction, role of smc under normal conditions, blood pressure, distribution of oxygenated blood through systemic circulation

Biochem/physiol Actions

Aorta

Preparation Note

  • 2nd passage, >500,000 cells in Rabbit Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
  • Can be cultured at least 6 doublings

Please refer to the RbAOSMC Culture Protocol.

Other Notes

Rabbit Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO


存储类别

11 - Combustible Solids

WGK

WGK 3

闪点 (F)

Not applicable

闪点 (°C)

Not applicable



历史批次信息供参考:

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