Anti-Serotonin 5-HT_2B Receptor antibody produced in rabbit

Multiplbe genes encode different subtypes of serotonin (5HT) receptor and are species specific. HTR2B is expressed in mammalian brain and is localized to GABA (γ-aminobutyric acid) producing neurons of dorsal hypothalamic nucleus. The HTR2B gene is mapped to human chromosome 2q37.1.

The Serotonin 5-HT_2B Receptor regulates cardiomyocyte development and growth. Activation of 5-HT_2B receptors may also contribute to initiation of sleep and to theta generation during W and PS under physiological conditions.

synthetic peptide corresponding to the second extracellular loop of human serotonin 5-HT_2B receptor, conjugated KLH. The immunizing peptide has 80% homology with the rat gene and 93% homology with the mouse gene.

The functions of serotonin (5HT) receptors are associated with sleep disorders, anxiety, depression and schizophrenia.

solution in phosphate buffered saline containing ≤0.1% sodium azide

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