S0501
硝普钠 二水合物
别名:
SNP, 五氰基亚硝酰基铁酸钠, 亚硝基铁氰化钠, 硝普酸钠
SMILES字符串
O.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
InChI
1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;
InChI key
OIRZWVYIQXBRFC-UHFFFAOYSA-N
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生化/生理作用
体内释放 NO，从而活化鸟苷酸环化酶、ADP-核糖基转移酶和环氧合酶并抑制脂肪氧合酶。诱导血管舒张以及抑制血小板聚集。
其他说明
This product has been replaced by 228710-Sigma-Aldrich | Sodium nitroferricyanide(III) dihydrate, ACS reagent, 99% | Na2[Fe(CN)5NO]
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
B Brüne et al.
The Journal of biological chemistry, 264(15), 8455-8458 (1989-05-25)
Sodium nitroprusside is a vasodilator and an inhibitor of platelet activation. It is thought that these effects are mediated by the spontaneous release of nitric oxide and stimulation of cytosolic guanylate cyclase. We have found that sodium nitroprusside (5-200 microM)
C M Roos et al.
Journal of applied physiology (Bethesda, Md. : 1985), 77(1), 51-57 (1994-07-01)
We localized the sites of vasodilation of inhaled nitric oxide (NO), a selective pulmonary vasodilator, and sodium nitroprusside (SNP) in isolated rat lungs. The sites were determined by analyzing the arterial, venous, and double-occlusion data with a two-resistor (small arteries
M Maccarrone et al.
Biochemical and biophysical research communications, 219(1), 128-133 (1996-02-06)
The nitric oxide (N0-releasing agents sodium nitroprusside (SNP) and S-nitroso-N-acetylpenicillamine (SNAP) inhibit dioxygenase activity of lipoxygenase in human platelets and human CHP100 neuroblastoma cells, leading the latter to necrosis. The effect of both NO-donors on the dioxygenase reaction was investigated
D Salvemini et al.
The Journal of clinical investigation, 97(11), 2562-2568 (1996-06-01)
We have evaluated the contributions of nitric oxide (NO) and prostacyclin (PGI2) in the in vivo antiplatelet effects of clinically useful nitrovasodilators. In rats, intravenous infusion of three NO donors, glyceryl trinitrate, sodium nitroprusside, or 3'-morpholinosydnonimine, the stable metabolite of
Feelisch, M.
Journal of Cardiovascular Pharmacology, 17, S25-S25 (1991)
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