S0520
晒代胱胺 二盐酸盐
>98% (TLC), suitable for ligand binding assays
别名:
2,2′-diselenobis-Ethanamine hydrochloride (1:2)
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关于此项目
经验公式（希尔记法）:
C4H12N2Se2 · 2HCl
化学文摘社编号:
分子量:
318.99
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.26
MDL number:
产品名称
晒代胱胺 二盐酸盐, powder
assay
>98% (TLC)
Quality Level
form
powder
technique(s)
ligand binding assay: suitable
color
yellow to orange
solubility
H2O: soluble, clear to slightly hazy
SMILES string
NCC[Se][Se]CCN.[H]Cl.[H]Cl
InChI
1S/C4H12N2Se2.ClH/c5-1-3-7-8-4-2-6;/h1-6H2;1H
InChI key
PKRYDZYGNSZBHO-UHFFFAOYSA-N
General description
盐酸硒胱胺有可能阻断甲型和乙型流感病毒相关的 RNA 依赖性 RNA 聚合酶的活性。
Application
硒代胱胺二盐酸盐在体外已被用于测定其对 PP2A 磷酸酶活性的影响。它也被用作二硫键裂解试剂二硫苏糖醇 (DTT) 的催化剂。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Y Hou et al.
Biochemical and biophysical research communications, 228(1), 88-93 (1996-11-01)
Seleno compounds such as selenocystamine and seleno-D, L-cystine were found to catalyze the decomposition of S-nitrosothiols (e.g. S-nitroso-glutathione and S-nitroso-N-acetyl-D, L-penicillamine) in the presence of different thiols (e.g. glutathione, N-acetyl-D-penicillamine and 2-mercaptoethanol), and liberate nitric oxide. It was also found
Transferrin serves as a mediator to deliver organometallic ruthenium (II) anticancer complexes into cells
Guo W, et al.
Inorganic Chemistry, 52(9), 5328-5338 (2013)
Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer?s disease model
Corcoran NM, et al.
Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia, 17(8), 1025-1033 (2010)
L Chen et al.
Free radical biology & medicine, 19(6), 713-724 (1995-12-01)
A selenium (Se)-containing immunoconjugate of a human anti-erythrocyte membrane antibody (Ab-Se) has been synthesized via oxidation of the carbohydrate moieties of the antibody and covalent coupling with selenocystamine. The isolated Ab-Se immunoconjugate is shown to be more hemolytic than is
Wansik Cha et al.
Biomaterials, 28(1), 19-27 (2006-09-09)
Novel nitric oxide (NO) generating polymeric materials possessing immobilized organoselenium species are described. These materials mimic the capability of small organoselenium molecules as well as a known selenium-containing enzyme, glutathione peroxidase (GPx), by catalytically decomposing S-nitrosothiols (RSNO) into NO and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S0520-25MG | 04061832424460 |
| S0520-100MG | 04061832424453 |
| S0520-1G | 04061835359141 |
| S0520-250MG | 04061835359158 |
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