S0520
晒代胱胺 二盐酸盐
>98% (TLC), suitable for ligand binding assays
别名:
2,2′-diselenobis-Ethanamine hydrochloride (1:2)
产品名称
晒代胱胺 二盐酸盐, powder
方案
>98% (TLC)
质量水平
表单
powder
技术
ligand binding assay: suitable
颜色
yellow to orange
溶解性
H2O: soluble, clear to slightly hazy
SMILES字符串
NCC[Se][Se]CCN.[H]Cl.[H]Cl
InChI
1S/C4H12N2Se2.ClH/c5-1-3-7-8-4-2-6;/h1-6H2;1H
InChI key
PKRYDZYGNSZBHO-UHFFFAOYSA-N
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一般描述
盐酸硒胱胺有可能阻断甲型和乙型流感病毒相关的 RNA 依赖性 RNA 聚合酶的活性。
应用
硒代胱胺二盐酸盐在体外已被用于测定其对 PP2A 磷酸酶活性的影响。它也被用作二硫键裂解试剂二硫苏糖醇 (DTT) 的催化剂。
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Yajun Weng et al.
Biomaterials, 32(5), 1253-1263 (2010-11-26)
Immobilization of selenocystamine on TiO(2) film deposited on silicon wafer and 316 stainless steel stents for catalytic generation of nitric oxide was described. Polydopamine was used as the linker for immobilization of selenocystamine to the TiO(2) surface. In vitro stability
R Singh et al.
Analytical biochemistry, 232(1), 86-91 (1995-11-20)
The reduction of a disulfide to thiols, using sodium borohydride or dithiothreitol as reductant, is catalyzed by selenol. The rates of reduction of oxidized glutathione and bis(2-hydroxyethyl) disulfide by sodium borohydride are accelerated using a catalytic amount of selenol (8
W A Prütz
Zeitschrift fur Naturforschung. C, Journal of biosciences, 50(3-4), 209-219 (1995-03-01)
Selenite and selenocystamine [(CyaSe)2] efficiently activate the decomposition of H2O2 by GSH and by other thiols, as demonstrated using a leuco crystal violet POD-based H2O2 assay which is applicable (unlike other assays) also in presence of thiols. The GPx-like activities
Glutathione peroxidase activity of D,L-seleno-cystine and selenocystamine.
K Yasuda et al.
Biochemical and biophysical research communications, 96(1), 243-249 (1980-09-16)
L Tatum et al.
Biological trace element research, 77(3), 241-249 (2001-02-24)
The purpose of this study was to investigate the ameliorating effects of dietary copper supplementation on selenium toxicity. Nine groups (n = 6) of weanling Fischer 344 female rats were randomly assigned to treatment groups and fed diets containing nontoxic
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