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Merck
CN

S0520

晒代胱胺 二盐酸盐

>98% (TLC), suitable for ligand binding assays

别名:

2,2′-diselenobis-Ethanamine hydrochloride (1:2)

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关于此项目

经验公式(希尔记法):
C4H12N2Se2 · 2HCl
化学文摘社编号:
分子量:
318.99
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.26
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产品名称

晒代胱胺 二盐酸盐, powder

方案

>98% (TLC)

质量水平

表单

powder

技术

ligand binding assay: suitable

颜色

yellow to orange

溶解性

H2O: soluble, clear to slightly hazy

SMILES字符串

NCC[Se][Se]CCN.[H]Cl.[H]Cl

InChI

1S/C4H12N2Se2.ClH/c5-1-3-7-8-4-2-6;/h1-6H2;1H

InChI key

PKRYDZYGNSZBHO-UHFFFAOYSA-N

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一般描述

盐酸硒胱胺有可能阻断甲型和乙型流感病毒相关的 RNA 依赖性 RNA 聚合酶的活性。

应用

硒代胱胺二盐酸盐在体外已被用于测定其对 PP2A 磷酸酶活性的影响。它也被用作二硫键裂解试剂二硫苏糖醇 (DTT) 的催化剂。

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M S Stewart et al.
Free radical biology & medicine, 26(1-2), 42-48 (1999-01-16)
The cancer chemopreventive effect of selenium cannot be fully accounted for by the role of selenium as a component of the antioxidant enzyme glutathione peroxidase, which suggests that chemoprevention occurs by another mechanism. Several studies have shown that thiol oxidation
T Tabatabaie et al.
Toxicology and applied pharmacology, 141(2), 389-393 (1996-12-01)
Chronic benzaldehyde exposure is known to cause central nervous system (CNS) disturbances. Previous studies have shown that benzaldehyde causes the formation of reactive oxygen species (ROS) in rat synaptosomal fractions. Benzaldehyde has also been implicated in ROS formation in the
L Chen et al.
Free radical biology & medicine, 19(6), 713-724 (1995-12-01)
A selenium (Se)-containing immunoconjugate of a human anti-erythrocyte membrane antibody (Ab-Se) has been synthesized via oxidation of the carbohydrate moieties of the antibody and covalent coupling with selenocystamine. The isolated Ab-Se immunoconjugate is shown to be more hemolytic than is
Axel L Dessal et al.
Molecular pharmacology, 79(1), 24-33 (2010-10-01)
G protein-coupled receptors transduce signals through heterotrimeric G protein Gα and Gβγ subunits, both of which interact with downstream effectors to regulate cell function. Gβγ signaling has been implicated in the pathophysiology of several diseases, suggesting that Gβγ could be
Megan C Frost et al.
Biomaterials, 26(14), 1685-1693 (2004-12-04)
The current state-of-the-art with respect to the preparation, characterization and biomedical applications of novel nitric oxide (NO) releasing or generating polymeric materials is reviewed. Such materials show exceptional promise as coatings to prepare a new generation of medical devices with

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