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Merck
CN

S0575

Anti-SET (56-70) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-2PP2A, Anti-I2PP2A, Anti-IGAAD, Anti-IPP2A2, Anti-PHAPII, Anti-SET Isoform 2 of Protein SET, Anti-TAF-I, Anti-TAF-Iβ

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~32 kDa

species reactivity

human

technique(s)

western blot: 1:500-1:2,000

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SET(6418)

General description

SET (SET nuclear oncogene) is an oncoprotein. It is also termed as I2PP2A (protein phosphatase type 2A inhibitor II)/TAF-1β. It is located on human chromosome 9q34.11. SET belongs to the inhibitor of histone acetyltransferase (INHAT) complex, that blocks histone acetylation.

Immunogen

synthetic peptide corresponding to amino acids 56-70 of human SET

Application

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Biochem/physiol Actions

SET (SET nuclear oncogene) oncoprotein participates in several aspects related to chromatin structure. It is considered as a histone chaperone, which is essential for chromatin transcription and a vital modulator of chromosome condensation.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization
Yokota N, et al.
Oncogene, 23(19), 3444-3444 (2004)
SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation
Almeida L O, et al.
Testing, 8(16), 26802-26802 (2017)

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