S0752
(±)-Synephrine
≥98%
别名:
1-(4-Hydroxyphenyl)-2-methylaminoethanol, 4-Hydroxy-α-(methylaminomethyl)benzyl alcohol
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关于此项目
线性分子式:
HOC6H4CH(CH2NHCH3)OH
化学文摘社编号:
分子量:
167.21
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
202-300-9
MDL number:
InChI key
YRCWQPVGYLYSOX-UHFFFAOYSA-N
InChI
1S/C9H13NO2/c1-10-6-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3
SMILES string
OC1=CC=C(C(O)CNC)C=C1
assay
≥98%
mp
187 °C (dec.) (lit.)
storage temp.
2-8°C
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)
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Application
(±)-Synephrine has been used as an alkaloid to investigate its in vitro antiviral, antibacterial, antifungal and cytotoxicity activities.
Biochem/physiol Actions
Synephrine is naturally found in citrus plants belonging to the Rutaceae family. It is a sympathomimetic alkaloid. Synephrine has 3 isomeric forms, such as m-synephrine, p-synephrine and o-synephrine. It exhibits β-adrenergic properties.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Claudio Medana et al.
Analytical and bioanalytical chemistry, 405(2-3), 1105-1113 (2012-12-05)
The occurrence of some cases of positive results in anti-doping analysis of octopamine requires clarification as to whether its methylated derivative synephrine could be a metabolic precursor of octopamine itself. Synephrine is a natural phenylethylamine derivative present in some food
Katsuhisa Ozaki et al.
Nature communications, 2, 542-542 (2011-11-17)
Swallowtail butterflies belonging to the family of Papilionidae selectively utilize a limited number of plants from a single or a few families. Female butterflies lay eggs on their host only when they detect specific chemicals through their foreleg chemosensilla while
C M Brown et al.
British journal of pharmacology, 93(2), 417-429 (1988-02-01)
1. The activities of the (-)- and (+)-forms of m- and p-octopamine and m- and p-synephrine on alpha 1-adrenoceptors from rat aorta and anococcygeus and alpha 2-adrenoceptors from rabbit saphenous vein were compared with those of noradrenaline (NA). 2. The
Shun-ichi Ishiuchi et al.
The journal of physical chemistry. A, 115(37), 10363-10369 (2011-08-09)
In our previous work, we found that synephrine has six conformers in the gas phase, while adrenaline, which is a catecholamine and has the same side chain as synephrine, has been reported to have only two conformers. To determine the
Comprehensive Natural Products II: Chemistry and Biology (2010)
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