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S1153

N-琥珀酰-Leu-Tyr-7-胺基-4-甲基香豆素

Name: N-琥珀酰-Leu-Tyr-7-胺基-4-甲基香豆素
Brand: SIGMA

calpain substrate, solid

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关于此项目

经验公式（希尔记法）:

C₂₉H₃₃N₃O₈

化学文摘社编号:

94367-20-1

分子量:

551.59

UNSPSC Code:

12352204

PubChem Substance ID:

24899464

NACRES:

NA.32

MDL number:

MFCD00057900

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属性

产品名称

N-琥珀酰-Leu-Tyr-7-胺基-4-甲基香豆素, calpain substrate

Quality Level

200

form

solid

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)CCC(O)=O)C(=O)NC(Cc1ccc(O)cc1)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2

InChI

1S/C29H33N3O8/c1-16(2)12-22(31-25(34)10-11-26(35)36)29(39)32-23(14-18-4-7-20(33)8-5-18)28(38)30-19-6-9-21-17(3)13-27(37)40-24(21)15-19/h4-9,13,15-16,22-23,33H,10-12,14H2,1-3H3,(H,30,38)(H,31,34)(H,32,39)(H,35,36)

InChI key

RIYLNECMTVNMSO-UHFFFAOYSA-N

说明

General description

猪钙蛋白酶I和II的底物。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Inhibition of chicken calpain II by proteins of the cystatin superfamily and alpha 2-macroglobulin.

C Crawford

The Biochemical journal, 248(2), 589-594 (1987-12-01)

Inhibition of chicken calpain II by proteins of the cystatin superfamily and alpha 2-macroglobulin was investigated. Human liver cystatins A and B, human cystatin C, chicken cystatin and rat T-kininogen were found not to be inhibitory. Inhibition was, however, observed

Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates.

T Sasaki et al.

The Journal of biological chemistry, 259(20), 12489-12494 (1984-10-25)

Homogeneous porcine calpain (Ca2+-dependent cysteine proteinase) was found to hydrolyze a variety of peptides and synthetic substrates. Leu-Trp-Met-Arg-Phe-Ala, eledoisin-related peptide, alpha-neoendorphin, angiotensin I, luteinizing hormone-releasing hormone, neurotensin, dynorphin, glucagon, and oxidized insulin B chain were cleaved with a general preference

Nepetin reduces virulence factors expression by targeting ClpP against MRSA-induced pneumonia infection.

Shisong Jing et al.

Virulence, 13(1), 578-588 (2022-04-02)

The resistance of Staphylococcus aureus (S. aureus) to various antibiotics has increased dramatically due to the misuse of antibiotics, and thus the development of new anti-infective drugs with new targets is urgently needed to combat resistance. Caseinolytic peptidase P is

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全球贸易项目编号

货号	GTIN
S1153-5MG	04061836908898
S1153-50MG	04061834742494
S1153-10MG	04061832910116