产品名称
Monoclonal Anti-SERCa2 ATPase antibody produced in mouse, clone IID8
conjugate
unconjugated
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
IID8, monoclonal
species reactivity
bovine, canine, rat, human, pig, rabbit
technique(s)
immunocytochemistry: suitable
immunohistochemistry (frozen sections): 1:500
indirect immunofluorescence: suitable
western blot: 1:500-1:5,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ATP2A2(488)
rat ... Atp2a2(29693)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
purified canine cardiac sarcoplasmic reticulum.
Other Notes
Not suitable for immunoblotting in rat SERCA2.
Physical form
Supplied as a solution in PBS containing 0.05% sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Haibin Gong et al.
Experimental and therapeutic medicine, 12(3), 1355-1362 (2016-09-08)
The study was conducted to examine the effects of ICI 118,551 on the systolic function of cardiac muscle cells of rats in heart failure and determine the molecular mechanism of selective β2-adrenergic receptor (β2-AR) antagonist on these cells. The chronic
Luca Hegedũs et al.
International journal of cancer, 140(12), 2758-2770 (2016-11-05)
Oncogenic mutations of BRAF lead to constitutive ERK activity that supports melanoma cell growth and survival. While Ca2+ signaling is a well-known regulator of tumor progression, the crosstalk between Ca2+ signaling and the Ras-BRAF-MEK-ERK pathway is much less explored. Here
Luca Hegedüs et al.
Frontiers in oncology, 7, 95-95 (2017-06-10)
Several new therapeutic options emerged recently to treat metastatic melanoma; however, the high frequency of intrinsic and acquired resistance among patients shows a need for new therapeutic options. Previously, we identified the plasma membrane Ca2+ ATPase 4b (PMCA4b) as a
Ning Li et al.
Traffic (Copenhagen, Denmark), 18(4), 232-241 (2017-02-06)
Darier's disease (DD) is an autosomal dominantly inherited skin disorder caused by mutations in sarco/endoplasmic reticulum Ca2+ -ATPase 2 (SERCA2), a Ca2+ pump that transports Ca2+ from the cytosol to the endoplasmic reticulum (ER). Loss of desmosomes and keratinocyte cohesion
Mirella Telles Salgueiro Barboni et al.
Progress in retinal and eye research, 95, 101137-101137 (2022-11-21)
Duchenne muscular dystrophy (DMD) is caused by X-linked inherited or de novo DMD gene mutations predominantly affecting males who develop early-onset muscle degeneration, severely affecting their quality of life and leading to reduced life expectancy. DMD patients may also develop
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