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About This Item
线性分子式:
C11H14ClN·HCl
CAS Number:
分子量:
232.15
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
方案
≥98% (HPLC)
表单
solid
颜色
white
溶解性
H2O: 24 mg/mL
SMILES字符串
Cl.CN1CCc2cccc(Cl)c2CC1
InChI
1S/C11H14ClN.ClH/c1-13-7-5-9-3-2-4-11(12)10(9)6-8-13;/h2-4H,5-8H2,1H3;1H
InChI key
JKQKVNMNAIFCFS-UHFFFAOYSA-N
基因信息
human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)
应用
SKF 86466 was used to study adrenoceptor signaling in rat limbic seizure models.
生化/生理作用
SKF 86466 binds specifically to α2-adrenoceptors at pre- and post-junctional sites but was also reported to antagonize α1-aderenoceptors in humans. The structural similarity of receptors enables SKF 86466 binding to 5-HT1A receptors.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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