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Merck
CN

S166

Sigma-Aldrich

Saclofen

solid

别名:

β-(氨甲基)-4-氯苯乙磺酸

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关于此项目

经验公式(希尔记法):
C9H12ClNO3S
CAS Number:
分子量:
249.71
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.32
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表单

solid

质量水平

颜色

white

溶解性

0.1 M NaOH: 20 mg/mL

SMILES字符串

NCC(CS(O)(=O)=O)c1ccc(Cl)cc1

InChI

1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)

InChI key

JYLNVJYYQQXNEK-UHFFFAOYSA-N

应用

Saclofen已被用于阻止催产素对辣椒素诱导的谷氨酸自发兴奋性传递的抑制作用。
使用Saclofen作为GABAB受体拮抗剂以研究大鼠反复注射羟考酮的镇痛作用。

生化/生理作用

Saclofen可能具有交感神经系统依赖性抗炎作用。
Saclofen是巴氯芬的磺酸类似物,是一种选择性GABAB受体拮抗剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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