Monoclonal Anti-Sarcalumenin antibody produced in mouse

Sarcalumenin (SAR) is a Ca²⁺ binding protein. It is present in the longitudinal sarcoplasmic reticulum. It is expressed in the striated muscle cells.

purified rabbit sarcoplasmic reticulum membrane vesicles.

In mice, deletion of sarcalumenin increases resistance to fatigue and altered calcium handling properties. It is required in the maintenance of cardiac activities throughout endurance exercise training. It modulates the reuptake of Ca²⁺ into the sarcoplasmic reticulum. It also plays an important role in age-related cardiac malfunction.

Solution in phosphate buffered saline containing 0.05% sodium azide

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