Anti-phospho-Src (pTyr⁴¹⁸) antibody produced in rabbit

Src is a proto-oncogene that regulates neuronal functions, such as nerve cell differentiation. The Src kinase family structurally comprises of SH2, SH3 and kinase domains, as well as a negative regulatory C-terminal tail. Src has also been implicated in functions such as cell growth, development and cell-cell interactions . Anti-phospho-Src p(Tyr⁴¹⁸) antibody is specific for human, mouse, rat and chicken Src (60 kDa).

The sequence is conserved in human, mouse, chicken and frog.

synthetic phosphopeptide derived from the region of src that contains tyrosine 418, based on the sequence of human src.

Anti-phospho-Src p(Tyr⁴¹⁸) antibody is suitable for use in western blot (1:1,000 using human platelets or mouse NIH3T3 cells). The product may also be used for immunoprecipitation (1:1000 using HEK293 or HEL cell lysates ).

Solution in Dulbecco′s phosphate-buffered saline (without Mg²⁺ and Ca²⁺), pH 7.3, with 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide.

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