质量水平
方案
≥98% (HPLC)
溶解性
DMSO: >20 mg/mL
储存温度
2-8°C
SMILES字符串
COc1ccc(cc1)-n2nc(cc2-c3ccc(Cl)cc3)C(F)(F)F
InChI
1S/C17H12ClF3N2O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3
InChI key
PQUGCKBLVKJMNT-UHFFFAOYSA-N
基因信息
human ... PTGS1(5742), PTGS2(5743)
应用
生化/生理作用
SC-560 (5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole) is a non-steroidal anti-inflammatory drug (NSAID).[3] It is a lipophilic, diaryl heterocyclic compound.[4] SC-560 acts as an effective antiviral agent against hepatitis C virus (HCV).[5] It also has a potential to hinder prostaglandin E2 synthesis in neurons at nanomolar concentrations.[6]
SC-560 belongs to the diaryl heterocycle class of cyclooxygenase (COX) inhibitors. It exhibits anti-tumor and anti-proliferative activities.[7]
Selective cyclooxygenase-1 (COX-1) inhibitor, exhibiting 700-fold selectivity for COX-1 over COX-2.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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