S2189
SE 175
≥97%
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关于此项目
经验公式（希尔记法）:
C16H13NO6S
化学文摘社编号:
分子量:
347.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
InChI
1S/C16H13NO6S/c1-22-15(18)13-4-2-3-5-14(13)24-16(19)12-8-6-11(7-9-12)10-23-17(20)21/h2-9H,10H2,1H3
SMILES string
COC(=O)c1ccccc1SC(=O)c2ccc(CO[N+]([O-])=O)cc2
InChI key
JDIVRBDMTYQVOK-UHFFFAOYSA-N
assay
≥97%
shipped in
wet ice
storage temp.
−20°C
Quality Level
Application
SE 175 may be used in cell signaling studies.
Biochem/physiol Actions
An organic nitrate compound that acts as an NO donor in vivo following reductive transformation of the nitrate group to nitric oxide.
SE 175 is a nitrate compound that belongs to the same class as nitroglycerine. It acts as a vasodilator and has clinical use in the treatment of angina. NO donors also confer neuroprotection and relieve neuropathic pain.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Magda Rybczynska et al.
Vaccine, 38(33), 5337-5342 (2020-06-24)
Freezing of alum-based vaccines drastically alters their colloidal composition and leads to irreversible cluster formation. The loss of stability is well described, but the impact of frost damage on the functionality of the induced and secreted antibody repertoire has not
Gregory R J Thatcher et al.
Free radical biology & medicine, 37(8), 1122-1143 (2004-09-29)
Nitroglycerine has been used clinically in the treatment of angina for 130 years, yet important details on the mechanism of action, biotransformation, and the associated phenomenon of nitrate tolerance remain unanswered. The biological activity of organic nitrates can be said
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