S2501
亚精胺 三盐酸盐
From microbial,synthetic, ≥98% (TLC), nNOS inhibitor, powder
别名:
N-（3-氨基丙基）-1，4-丁二胺 三盐酸盐
Product Name
亚精胺 三盐酸盐, ≥98% (TLC)
生物来源
microbial
synthetic
质量水平
方案
≥98% (TLC)
表单
powder
mp
257-259 °C (lit.)
溶解性
water: 100 mg/mL, clear, colorless
储存温度
room temp
SMILES字符串
Cl[H].Cl[H].Cl[H].NCCCCNCCCN
InChI
1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
InChI key
LCNBIHVSOPXFMR-UHFFFAOYSA-N
基因信息
human ... NOS1(4842)
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一般描述
一氧化氮合酶（nNOS）基因位于人染色体 12q24.22 上。该酶参与一氧化氮的产生。
应用
亚精胺三盐酸盐已用于傅里叶变换红外光谱（FTIR）表征和zeta电位测量。
生化/生理作用
抑制神经元型一氧化氮合酶（nNOS）。结合并沉淀 DNA；刺激T4多核苷酸激酶活性。
抑制神经元型一氧化氮合酶（nNOS）。结合并沉淀DNA；可用于纯化DNA结合蛋白。刺激T4多核苷酸激酶活性。
免责声明
如果需要无菌溶液，则应采用无菌过滤而非高压灭菌。时间一长，亚精胺将发生脱氨基作用；溶液应采用冷冻保存。通常需要配制新溶液。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells.
Castro-Smirnov FA
Scientific Reports, 6, 36341-36341 (2016)
Neuronal Nitric Oxide Synthase (nNOS, NOS1) rs693534 and rs7977109 Variants and Risk for Migraine.
Garcia-Martin E
Headache, 55(9), 1209-1217 (2015)
Polyamines and its analogue modulates amyloid fibrillation in lysozyme: A comparative investigation.
Ayesha Kabir et al.
Biochimica et biophysica acta. General subjects, 1864(5), 129557-129557 (2020-02-12)
Polyamines can induce protein aggregation that can be related to the physiology of the cellular function. Polyamines have been implicated in protein aggregation which may lead to neuropathic and non neuropathic amyloidosis. Change in the level of polyamine concentration has
Evidence for the contribution of NOS1 gene polymorphism (rs3782206) to prefrontal function in schizophrenia patients and healthy controls.
Zhang Z
Neuropsychopharmacology, 40(6), 1383-1394 (2015)
Miao Cui et al.
STAR protocols, 1(2), 100049-100049 (2020-10-29)
Murine cardiomyocytes undergo proliferation, multinucleation, and polyploidization during the first 3 weeks of postnatal life, resulting in a mixture of diploid and tetraploid cardiomyocytes in the heart. Understanding the molecular differences between diploid and tetraploid cardiomyocytes from these processes has been
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