S2647
壮观霉素 二盐酸盐 五水合物
powder, γ-irradiated
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H24N2O7 · 2HCl · 5H2O
化学文摘社编号:
分子量:
495.35
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
244-554-3
MDL number:
InChI key
DCHJOVNPPSBWHK-UXXUFHFZSA-N
InChI
1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
SMILES string
O.O.O.O.O.Cl.Cl.CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O
biological source
synthetic (inorganic)
grade
Molecular Biology
sterility
γ-irradiated
form
powder
potency
≥500 μg per mg
storage condition
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
color
white to off-white
solubility
H2O: soluble at
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
protein synthesis | interferes
storage temp.
2-8°C
suitability
nonselective for Escherichia coli, nonselective for coliforms
Quality Level
正在寻找类似产品? 访问 产品对比指南
General description
Chemical structure: aminoglycoside
Application
Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.
Biochem/physiol Actions
作用机制：壮观霉素通过与细菌30S核糖体亚基结合并干扰肽基tRNA易位而抑制蛋白质合成和延伸。
抗性机制：rpsE（核糖体蛋白S5的基因）突变可阻止壮观霉素的结合。氨基糖苷-3′-腺苷转移酶基因（aadA）也能使细菌产生抗性。
抗菌谱：壮观霉素能够对抗革兰氏阴性和革兰氏阳性菌。
抗性机制：rpsE（核糖体蛋白S5的基因）突变可阻止壮观霉素的结合。氨基糖苷-3′-腺苷转移酶基因（aadA）也能使细菌产生抗性。
抗菌谱：壮观霉素能够对抗革兰氏阴性和革兰氏阳性菌。
Packaging
100MG
Preparation Note
直接在小瓶中用无菌水配制储存液 (10mg/mL)。储存液在 2-8°C 下可保存数周，在 -20°C 下可长期保存。
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Disclaimer
Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Susanna Ricci et al.
Infection and immunity, 70(9), 4968-4976 (2002-08-17)
Ferric uptake regulator (Fur) and Fur-like proteins form an important family of transcriptional regulators in many bacterial species. In this work we have characterized a Fur-like protein, the peroxide regulator PerR, in an M1 serotype of Streptococcus pyogenes. To determine
K Matsumoto et al.
Journal of bacteriology, 180(1), 100-106 (1998-01-09)
The psd gene of Bacillus subtilis Marburg, encoding phosphatidylserine decarboxylase, has been cloned and sequenced. It encodes a polypeptide of 263 amino acid residues (deduced molecular weight of 29,689) and is located just downstream of pss, the structural gene for
Praveen Kumar et al.
Journal of separation science, 35(4), 498-504 (2012-01-28)
The effect of mobile-phase constituents (pH and ionic strength) and chromatographic behaviour of ten aminoglycosides (streptomycin, dihydrostreptomycin, spectinomycin, apramycin, paramomycin, kanamycin A, gentamycin C1, gentamycin C2/C2a, gentamycin C1a and neomycin) in the bare silica, amino, amide and zwitterionic phases of
Amber M Hotto et al.
G3 (Bethesda, Md.), 1(7), 559-570 (2012-03-03)
Noncoding RNAs (ncRNA) are widely expressed in both prokaryotes and eukaryotes. Eukaryotic ncRNAs are commonly micro- and small-interfering RNAs (18-25 nt) involved in posttranscriptional gene silencing, whereas prokaryotic ncRNAs vary in size and are involved in various aspects of gene
Tarinee Tungsuchat-Huang et al.
Plant molecular biology, 76(3-5), 453-461 (2011-01-05)
Identification of a genetically stable Nicotiana tabacum (tobacco) plant with a uniform population of transformed plastid genomes (ptDNA) takes two cycles of plant regeneration from chimeric leaves and analysis of multiple shoots by Southern probing in each cycle. Visual detection
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持