S2876
精胺 四盐酸盐
powder or crystals, NMDA agonist/antagonist
别名:
N,N′-双(3-氨丙基)-1,4-丁二胺 四盐酸盐
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关于此项目
经验公式（希尔记法）:
C10H26N4 · 4HCl
化学文摘社编号:
分子量:
348.18
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
206-189-8
MDL number:
Beilstein/REAXYS Number:
3911771
Form:
powder or crystals
Quality level:
产品名称
精胺 四盐酸盐, powder or crystals
form
powder or crystals
Quality Level
mp
310-311 °C (dec.) (lit.)
solubility
water, high purity: 100 mg/ml
storage temp.
room temp
SMILES string
Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
InChI
1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
InChI key
XLDKUDAXZWHPFH-UHFFFAOYSA-N
Gene Information
human ... GRIN1(2902)
Application
四盐酸精胺用于沉淀新鲜冷冻乳腺癌组织、 涎腺存档组织、肾和甲状腺肿瘤 以及鸡红细胞的 DNA，以进行流式细胞分析。
用于从低盐缓冲液中沉淀 DNA。
Biochem/physiol Actions
多胺位点混合型 NMDA 激动-拮抗剂。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
多胺位点混合型 NMDA 激动-拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
精胺是一种多胺，来源于亚精胺，是真核生物细胞生长所必需的。它充当基因表达的调节剂，抑制DNA损伤并通过充当自由基清除剂来保护细胞免受损害。 在蛋白质组学研究中，精胺介导 DNA 结合蛋白快速结晶。
Preparation Note
四盐酸精胺在100mg / ml的水中生成澄清、无色至淡黄色水溶液。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
商品
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
相关内容
J Griffith et al.
Biochemistry, 24(1), 158-162 (1985-01-01)
The RecA protein of Escherichia coli, whether pure or in a crude cell lysate, will rapidly form small crystals (microcrystals) in the presence of low concentrations of spermidine. We describe the conditions of time, pH, and polyamine concentration over which
A S Jackson et al.
The British journal of nutrition, 40(3), 497-504 (1978-11-01)
1. Skinfold thickness, body circumferences and body density were measured in samples of 308 and ninety-five adult men ranging in age from 18 to 61 years. 2. Using the sample of 308 men, multiple regression equations were calculated to estimate
E Bergers et al.
Journal of clinical pathology, 49(11), 931-937 (1996-11-01)
Conflicting results have been reported concerning the prognostic value of DNA flow cytometric variables (DNA ploidy, DNA index, %S phase fraction) in breast cancer. Selection bias and differences in treatment may have contributed to these conflicting prognostic results. Differences in
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S2876-1G | 04061836920562 |
| S2876-5G | 04061836920661 |
| S2876-25G | 04061833622025 |
| S2876-10G | 04061833622018 |
| S2876-100G | 04061833631799 |